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ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Quinoline compounds >QUINOLINE-2-CARBONITRILE

QUINOLINE-2-CARBONITRILE

QUINOLINE-2-CARBONITRILE Basic information
Product Name:QUINOLINE-2-CARBONITRILE
Synonyms:quinolin-2-carbonitrile;QUINOLINE-2-CARBONITRILE;2-QUINOLINECARBONITRILE;2-Cyanoquinoline;2-Quinolinecarbonitrile ,97%;Quinaldonitrile;Quinoline-2-Carbinitrile;Quinolinecarbonitrile
CAS:1436-43-7
MF:C10H6N2
MW:154.17
EINECS:215-865-1
Product Categories:Building Blocks;Heterocyclic Building Blocks;Quinolines
Mol File:1436-43-7.mol
QUINOLINE-2-CARBONITRILE Structure
QUINOLINE-2-CARBONITRILE Chemical Properties
Melting point 93-95 °C (lit.)
Boiling point 160°C 23mm
density 1.21
refractive index 1.4820 (estimate)
Fp 160°C/23mm
storage temp. Inert atmosphere,Room Temperature
pka-0.56±0.40(Predicted)
form powder to crystal
color White to Orange to Green
Water Solubility Insoluble in water.
BRN 115213
Safety Information
Hazard Codes Xn,Xi
Risk Statements 20/21/22-36/37/38
Safety Statements 26-36
RIDADR 3439
WGK Germany 3
HazardClass 6.1
PackingGroup III
HS Code 2933499090
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
QUINOLINE-2-CARBONITRILE Usage And Synthesis
UsesQuinoline-2-carbonitrile is used to produce quinoline-2-carboxylic acid amide. It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.
Synthesis Reference(s)Journal of the American Chemical Society, 81, p. 4004, 1959 DOI: 10.1021/ja01524a046
General DescriptionMechanism of the photoinduced substitution reaction of 2-quinolinecarbonitrile in alcohols or ethers has been reported. Photoinitiated dimerization of 2-quinolinecarbonitrile in HCl-acidified 2-propanol/water has been investigated at 77K and 331K. Benzophenone-sensitization of 2-quinolinecarbonitrile has been reported to yield triazapentaphene.
QUINOLINE-2-CARBONITRILE Preparation Products And Raw materials
Raw materialsAcetonitrile-->POTASSIUM CYANIDE-->Benzoyl chloride-->Quinoline
Preparation ProductsQuinaldic acid-->2-Quinolinemethanamine-->N-methylquinolin-2-amine
Tag:QUINOLINE-2-CARBONITRILE(1436-43-7) Related Product Information
4-chloroquinoline-2-carbonitrile 8-HYDROXYQUINOLINE-2-CARBONITRILE QUINOLINE-2-CARBONITRILE 7,7,8,8-Tetracyanoquinodimethane ETHYL 4-CHLORO-8-CYANOQUINOXALINE-3-CARBOXYLATE 3-Cyanoquinoline 6-Fluoro-4-(trifluoromethyl)quinoline-2-carbonitrile ,97% 6-Cyanoquinoline 4-(Trifluoromethyl)quinoline-2-carbonitrile ,97% 2,3,5,6-Tetrafluoro-7,7,8,8-tetracyanoquinodimethane 2-Amino-4-methyl-quinoline-3-carbonitrile ,98% 11-OXO-2,3,6,7-TETRAHYDRO-1H,5H,11H-PYRANO[2,3-F]PYRIDO[3,2,1-IJ]QUINOLINE-10-CARBONITRILE 6-METHOXY-2-QUINOLINECARBONITR 2-CYANO-3-HYDROXYQUINOLINE 2-CYANO-3-BROMOQUINOLINE 6-BROMO-QUINOLINE-2-CARBONITRILE 2-CYANO-4-METHYLQUINOLINE 2-CYANO-3-METHYLQUINOLINE