| Company Name: |
SYNRYN PHARMA PVT LTD
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| Tel: |
+91 9392615244 |
| Email: |
sales@synryn.com |
| Products Intro: |
Product Name:Secosirolimus
CAS:148554-65-8
Purity:96% Package:50 mg
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| Company Name: |
China DongFan Chemical Co.,LTD
|
| Tel: |
86-0571-85151182 |
| Email: |
|
| Products Intro: |
Product Name:Linagliptin
CAS:148554-65-8
Purity:98% HPLC Package:10g:50g;100g;250g
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| | SECO RAPAMYCIN SODIUM SALT Basic information |
| | SECO RAPAMYCIN SODIUM SALT Chemical Properties |
| Melting point | 120-122°C | | storage temp. | Amber Vial, -20°C Freezer, Under Inert Atmosphere | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | color | Pale Yellow to Yellow | | Stability: | Light Sensitive |
| | SECO RAPAMYCIN SODIUM SALT Usage And Synthesis |
| Description | Rapamycin is a natural macrolide immunosuppressant that activates mTORC1. Seco Rapamycin (sodium salt) is a nonenzyme-dependent degradation product of rapamycin resulting from ester hydration followed by dehydration. It has less than 4% of the potency of rapamycin in a thymocyte proliferation assay. Rapamycin quickly degrades to two ring-opened products, including seco rapamycin, in the cytoplasm or in homogenates of Caco-2 cells. Like rapamycin, seco rapamycin is secreted from cells by P-glycoprotein and metabolized to a common dihydro species. While seco rapamycin poorly activates mTOR, it mimics rapamycin in its ability to inhibit the proteasome. | | Chemical Properties | Yellow Solid | | Uses | A metabolite of Sirolimus | | Uses | A decomposition product of Rapamycin (R124000). |
| | SECO RAPAMYCIN SODIUM SALT Preparation Products And Raw materials |
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