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| | 3-Amino-4-hydroxybenzenesulphonamide Basic information |
| | 3-Amino-4-hydroxybenzenesulphonamide Chemical Properties |
| Melting point | 199-201°C | | Boiling point | 454.5±55.0 °C(Predicted) | | density | 1.580±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | soluble in Methanol | | form | powder to crystal | | pka | 7?+-.0.20(Predicted) | | color | White to Gray to Brown | | CAS DataBase Reference | 98-32-8(CAS DataBase Reference) | | EPA Substance Registry System | Benzenesulfonamide, 3-amino-4-hydroxy- (98-32-8) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | HS Code | 2935.90.9500 | | HazardClass | IRRITANT |
| | 3-Amino-4-hydroxybenzenesulphonamide Usage And Synthesis |
| Chemical Properties | Light brown crystal | | Uses | 3-Amino-4-hydroxybenzenesulfonamide is a reagent used to synthesize antagonists for somatostatin receptor subtype 5 (SST5R). It also has utility in dye applications. | | Production Methods | 2-nitrochlorobenzene is sulfochlorinated with chlorosulfuric acid; the resulting sulfochloride is treated with ammonia to give 4-chloro-3-nitrobenzenesulfonamide; chlorine is replaced by hydroxyl by heating the product at 100 ℃ in aqueous sodium hydroxide solution. Finally, the hydroxybenzenesulfonamide is reduced with iron turnings to obtain 3-Amino-4-hydroxybenzenesulphonamide. |
| | 3-Amino-4-hydroxybenzenesulphonamide Preparation Products And Raw materials |
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