CYTOCHALASIN E

CYTOCHALASIN E Suppliers list
Company Name: Shaanxi Dideu Medichem Co. Ltd
Tel: +86-029-81138252 +86-18789408387
Email: 1057@dideu.com
Products Intro: Product Name:Cytochalasin E
CAS:36011-19-5
Purity:99% Package:1KG;1USD
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:Cytochalasin E
CAS:36011-19-5
Purity:98.00% Package:100 mg;500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Career Henan Chemica Co
Tel: +86-0371-86658258 15093356674;
Email: laboratory@coreychem.com
Products Intro: Product Name:CYTOCHALASIN E
CAS:36011-19-5
Purity:85.0-99.8% Package:1g;1USD
Company Name: Shaanxi Dideu Medichem Co. Ltd
Tel: +86-029-89586680 +86-18192503167
Email: 1026@dideu.com
Products Intro: Product Name:CYTOCHALASIN E USP/EP/BP
CAS:36011-19-5
Purity:99.9% Package:25kgs/Drum;200kgs/Drum Remarks:FDA GMP CEP Approved Manufacturer
Company Name: Dideu Industries Group Limited
Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Products Intro: Product Name:CYTOCHALASIN E
CAS:36011-19-5
Purity:99.9% Package:1g;1.1USD Remarks:FDA GMP CEP Approved Manufacturer

CYTOCHALASIN E manufacturers

  • Cytochalasin E
  • Cytochalasin E  pictures
  • $1.00 / 1KG
  • 2020-05-08
  • CAS: 36011-19-5
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 20T
CYTOCHALASIN E Basic information
Product Name:CYTOCHALASIN E
Synonyms:(7S,13E,16S,18R,19E)-6,7-Epoxy-18-hydroxy-16,18-dimethyl-10-phenyl-21,23-dioxa[13]cytochalasa-13,19-diene-1,17,22-trione;[7β,13E,16S,18R,19E]-6,7-Epoxy-18-hydroxy-16,18-dimethyl-10-phenyl-21,23-dioxa[13]cytochalasa-13,19-diene-1,17,22-trione;(7s,13e,16s,18r,19e)-18-dimethyl-10-phenyl;21,23-dioxa(13)cytochalasa-13,19-diene-1,17,22-trione,6,7-epoxy-18-hydroxy-16,;6,7-epoxy-10-phenyl-5,6,16,18-tetramethyl-21,23-dioxa-[13]cytochalas-13,19-die;CYTOCHALASIN 3;CYTOCHALASIN E;CYTOCHALASIN E, ASPERGILLUS CLAVATUS
CAS:36011-19-5
MF:C28H33NO7
MW:495.56
EINECS:252-835-7
Product Categories:antibiotic;Actin Inhibitors and ProbesCell Signaling and Neuroscience;Cell Signaling and Neuroscience;Cytoskeleton and Extracellular Matrix;Mold;Toxins and Venoms
Mol File:36011-19-5.mol
CYTOCHALASIN E Structure
CYTOCHALASIN E Chemical Properties
Melting point 206 °C
Boiling point 587.59°C (rough estimate)
density 1.2415 (rough estimate)
refractive index 1.6290 (estimate)
storage temp. -20°C
solubility DMF: 11 mg/ml; DMF:PBS (pH7.2) (1:30): 0.03 mg/ml; DMSO: 10 mg/ml; Ethanol: 2 mg/ml
form White solid.
pka11.22±0.70(Predicted)
BRN 1096975
LogP1.920 (est)
Safety Information
Hazard Codes T+,T
Risk Statements 26/27/28-63
Safety Statements 28-36/37-45
RIDADR UN 1544 6.1/PG 2
WGK Germany 3
RTECS HA5360000
10
HazardClass 6.1(a)
PackingGroup I
HS Code 29349990
Hazardous Substances Data36011-19-5(Hazardous Substances Data)
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
CYTOCHALASIN E Usage And Synthesis
DescriptionThe cytochalasins are cell-permeable fungal metabolites which inhibit actin polymerization. This interferes with such diverse processes as cell movement, growth, phagocytosis, degranulation, and secretion. Cytochalasin E is an epoxide-containing analog of cytochalasin B which potently and selectively inhibits the growth of endothelial cells (IC50 < 1 nM), impairing angiogenesis and tumor growth. This cytochalasin does not inhibit glucose transport or HIV-1 protease activity.
Chemical Propertieswhite powder
UsesCytochalasin E has been used as:
  • a toxin to study its effects on avocado plants
  • a component of the incubating medium in feline junctional adhesion molecule 1 (fJAM-1) expression assay
  • an inhibitor of actin polymerization to study its effects on mitochondria uptake by mice endothelial cells

UsesCytochalasin E is a fungal metabolite which has been shown to exhibit antimicrobial and antibacterial effects. Cytochalasin E is a microfilament inhibitor enhancing the low-affinity Fc epsilon receptor (CD23) expression.
UsesCytochalasin E is one of a family of potent mycotoxins produced by a range of fungi. All members of the class exhibit profound effects on cytoskeletal proteins, resulting in pronounced morphogenic changes in animals and plants. Despite the common mode of action, there is evidence that individual members display diverse selectivity. Specifically, cytochalasin E acts as an angiogenesis inhibitor and, unlike other cytochalasins, does not inhibit glucose transport.
DefinitionChEBI: A natural product found in Arthrinium sacchari.
Biochem/physiol ActionsCytochalasin E is an epoxide that exhibits anti-proliferative activity in endothelial cells in vitro. It also participates in inhibiting tumor growth and angiogenesis in vivo. Cytochalasin E also possesses antimicrobial and antiviral properties.
CYTOCHALASIN E Preparation Products And Raw materials
Tag:CYTOCHALASIN E(36011-19-5) Related Product Information
CYTOCHALASIN B, DIHYDRO cytochalasi CYTOCHALASIN D CYTOCHALASIN C CYTOCHALASIN A (R)-(-)-1-Amino-2-propanol TRANS-3-HEXEN-1-OL 2-AMINOHEPTANE TERT-AMYL METHYL ETHER N-(2-METHOXYETHYL)METHYLAMINE 4-(N-BUTYLAMINO)-1-BUTANOL isobutoxypropanol 4-AMINO-2-BUTANOL 2-METHOXY-2-METHYL-PROPYLAMINE N-SEC-BUTYL-N-PROPYLAMINE (S)-2-Aminooctane 2,3-EPOXY-2-METHYLBUTANE 2-AZACYCLONONANONE