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ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Endocrinology & Hormones >RAAS inhibitors >ENALAPRILAT DIHYDRATE

ENALAPRILAT DIHYDRATE

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ENALAPRILAT DIHYDRATE Suppliers list
Company Name: Henan Fengda Chemical Co., Ltd
Tel: +86-371-86557731 +86-13613820652
Email: info@fdachem.com
Products Intro: Product Name:ENALAPRILAT DIHYDRATE
CAS:84680-54-6
Purity:99% Package:1KG;32USD|1000KG;1.3USD
Company Name: career henan chemical co
Tel: +86-0371-86658258
Email: sales@coreychem.com
Products Intro: Product Name:ENALAPRILAT DIHYDRATE
CAS: 84680-54-6
Purity:99% Package:1kg;1USD
Company Name: Hubei xin bonus chemical co. LTD
Tel: 86-13657291602
Email: linda@hubeijusheng.com
Products Intro: Product Name:ENALAPRILAT DIHYDRATE
CAS:84680-54-6
Purity:0.99 Package:5KG;1KG
Company Name: Standardpharm Co. Ltd.
Tel: 86-714-3992388
Email: overseasales1@yongstandards.com
Products Intro: Product Name:Enalapril EP Impurity C
Purity:0.99 Package:10mg;25mg;50mg;100mg
Company Name: BOC Sciences
Tel: +1-631-485-4226
Email: inquiry@bocsci.com
Products Intro: Product Name:Enalaprilat Dihydrate
CAS:84680-54-6
Purity:>98% Package:250mg Remarks:BOC Sciences also provides custom synthesis services for Enalaprilat Dihydrate.

ENALAPRILAT DIHYDRATE manufacturers

  • ENALAPRILAT DIHYDRATE
  • ENALAPRILAT DIHYDRATE pictures
  • $32.00 / 1KG
  • 2024-04-15
  • CAS:84680-54-6
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: g-kg-tons, free sample is available
  • ENALAPRILAT DIHYDRATE
  • ENALAPRILAT DIHYDRATE pictures
  • $793.70 / 10g
  • 2021-11-02
  • CAS:84680-54-6
  • Min. Order: 10g
  • Purity: 99%
  • Supply Ability: 400G
  • Enalaprilat Dihydrate
  • Enalaprilat Dihydrate pictures
  • $0.00 / 1g/Bag
  • 2021-09-29
  • CAS:84680-54-6
  • Min. Order: 1g
  • Purity: 98%-101%
  • Supply Ability: 500G
ENALAPRILAT DIHYDRATE Basic information
Product Name:ENALAPRILAT DIHYDRATE
Synonyms:(S)-1-[N-[1-(CARBOXY)-3-PHENYLPROPYL]-L-ALANYL]-L-PROLINE, DIHYDRATE;MK-422;ENALAPRILAT DIHYDRATE;ENALAPRILATE;Enalaprilate USP25;ENALAPRILAT USP;Enalaprilat (300 mg);Enalaprilic Acid Dihydrate
CAS:84680-54-6
MF:C18H26N2O6
MW:366.41
EINECS:689-724-1
Product Categories:Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Inhibitors
Mol File:84680-54-6.mol
ENALAPRILAT DIHYDRATE Structure
ENALAPRILAT DIHYDRATE Chemical Properties
Melting point 151-159°C
alpha [α]D25 -53.0～-56.0゜ (c=1, CH3OH) (Calculated on dehydrous basis)
storage temp. 2-8°C
solubility H2O: soluble14mg/mL at 60°C (warming for 5 minutes)
color White to Off-White
CAS DataBase Reference84680-54-6(CAS DataBase Reference)
EPA Substance Registry SystemL-Proline, N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-, hydrate (1:2) (84680-54-6)
Safety Information
WGK Germany 3
RTECS TW3590600
HS Code 2933995300
MSDS Information
ENALAPRILAT DIHYDRATE Usage And Synthesis
DescriptionAngiotensin-converting enzyme (ACE) converts angiotensin I to angiotensin II, a peptide hormone that impacts vascular smooth muscle tone and renal salt exchange, driving hypertension. Enalaprilat is the active metabolite of enalapril , an ACE inhibitor with roles in the management of hypertension, congestive heart failure, myocardial infarction, and diabetic nephropathies.. Enalaprilat is esterified with ethanol to produce enalapril in order to enable oral activity and subsequently metabolized in vivo to the active form by various esterases. Enalaprilat is reported to inhibit ACE activity with an IC50 value of 5.8 nM in vitro.
Chemical PropertiesWhite Solid
UsesActive metabolite of Enalapril. A nonsulfhydryl dipeptide angiotensin converting enzyme (ACE) inhibitor. Enalapril EP Impurity C (Dihydrate).
Usesanthelmintic
DefinitionChEBI: The dihydrate form of enalaprilat, an angiotensin-converting enzyme (ACE) inhibitor that is used (often in the form of its prodrug, enalapril) in the treatment of hypertension and heart failure, for reduction of proteinuria and renal disease in patients wi h nephropathies, and for the prevention of stroke, myocardial infarction, and cardiac death in high-risk patients. Unlike enalapril, enalaprilat is not absorbed by mouth but is administered by intravenous injection.
Biochem/physiol ActionsEnalapril, the ethyl ester of?enalaprilat exhibits slight pharmacological activity until it is hydrolyzed in the liver to?enalaprilat. Enalaprilat, a IV form of an angiotensin-converting-enzyme inhibitor (ACE) prevents the transformation of angiotensin I to angiotensin II, a potent vasoconstrictor.
ENALAPRILAT DIHYDRATE Preparation Products And Raw materials
Tag:ENALAPRILAT DIHYDRATE(84680-54-6) Related Product Information
Enalaprilat Triphosgene Ethyl trans-3-Benzoylacrylate Enalapril EP IMpurity A (SSR) L-Proline (R,S,S)-Enalapril L-Alanine Enalapril diketopiperazine (αS)-Cyclohexanebutanoic Acid α-[[(1S)-1-Carboxyethyl]aMino] cyclohexanebutanoic Acid α-Ethyl Ester Ethyl 3-benzoylacrylate Phenylsilane CHLOROPHENYLSILANE 97 Dimethylimidazole Phenyltrichlorosilane MOEXIPRIL HYDROCHLORIDE Fosinopril sodium CILAZAPRIL Belinostat (PXD101)