- Sodium orthovanadate
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- $0.00 / 25KG
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2023-08-15
- CAS:13721-39-6
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 50000KG/month
- Sodium Orthovanadate
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- $50.00 / 25Kg/Drum
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2023-07-25
- CAS:13721-39-6
- Min. Order: 25KG
- Purity: 99%min
- Supply Ability: 100tons/month
- Sodium orthovanadate
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- $10.00 / 1KG
-
2021-11-12
- CAS:13721-39-6
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 5tons
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| | Sodium orthovanadate Basic information |
| | Sodium orthovanadate Chemical Properties |
| Hazard Codes | Xn | | Risk Statements | 20/21/22 | | Safety Statements | 22-36 | | RIDADR | UN3285 | | WGK Germany | 3 | | RTECS | YW1120000 | | TSCA | Yes | | HazardClass | 6.1 | | PackingGroup | III | | HS Code | 28419030 |
| | Sodium orthovanadate Usage And Synthesis |
| Chemical Properties | It forms colourless hexagonal columnar crystals that are soluble in water but insoluble in ethanol. | | Uses | Sodium Orthovanadate is an inhibitor of several phosphatases and kinases. General inhibitor of tyrosine phosphatases, a large family of enzymes that catalyze the removal of phosphate groups from tyrosine residues. | | Uses | Sodium orthovanadate (Na3VO4) can be used as a metal precursor in the synthesis of:
Vanadium-MCM-48 (V-MCM-48) by anion-exchange method. V-MCM-48 is used as a catalyst in oxidation of styrene to benzaldehyde.
Nanorods of vanadium oxide particles by glycothermal method.
Yttrium vanadate (YVO4) doped with colloidal europium. | | Definition | ChEBI: Trisodium vanadate is an inorganic sodium salt of formula Na3VO4 containing the tetrahedral VO4(3-) It has a role as an EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor, a radiation protective agent, an apoptosis inducer and an antineoplastic agent. It contains a vanadate(3-). | | Preparation | Sodium orthovanadate is produced by dissolving vanadium(V) oxide in a solution of sodium hydroxide:
V2O5 + 6 NaOH → 2 Na3VO4 + 3 H2O
The salt features tetrahedral VO3-4 anion centers linked to octahedral Na+ cation sites. | | Hazard | Poison by ingestion. | | Biological Activity | Inhibitor of protein tyrosine phosphatases, alkaline phosphatases and ATPases. | | Biochem/physiol Actions | Sodium orthovandate suppresses the activation of p53-mediated apoptosis triggered in response to radiation. It reduces the detrimental effects of hematopoietic syndrome, hematopoiesis and delayed genotoxic effects of induced by total body irradiation of mice.24 In combination with menadione, orthovandate prevents the migration of detached human glioma cells in response to anti-cancer drugs.25 | | Safety Profile | Poison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of VOx and NazO. See also VANADIUM COMPOUNDS. | | storage | Store at RT |
| | Sodium orthovanadate Preparation Products And Raw materials |
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