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ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Quinoline compounds >4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline

4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline

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Products Intro: Product Name:4-chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline
CAS:99010-64-7
Purity:98%(Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
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Products Intro: Product Name:4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline
CAS:99010-64-7
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CAS:99010-64-7
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CAS:99010-64-7
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4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline Basic information
Product Name:4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline
Synonyms:4-CHLORO-1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINE;4-CHLORO-1-ISOBUTYL-1H-IMIDAZOBEN[4,5-C]QUINOLINE;1-[2-METHYLPROPYL]-1H-2-CHLOROIMIDAZO-[4,5-C]QUINOLINE;1H-IMIDAZO[4,5-C]QUINOLINE, 4-CHLORO-1-(2-METHYLPROPYL);4-Chloro-1-(2-methylpropyl)-1H-imidazo-(4,5c)quinolinone;2-CHLORO-1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINONE;1H-Imidazo[4,5-c]quinoline,;4-CHLORO-1-ISOBUTYL-1H-IMIBENZO(4,5-C)QUINOLINE
CAS:99010-64-7
MF:C14H14ClN3
MW:259.73
EINECS:619-386-2
Product Categories:Quinolines, Quinazolines and derivatives;Intermediates of Imiquimod;API intermediates
Mol File:99010-64-7.mol
4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline Structure
4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline Chemical Properties
Melting point 139-140 °C(Solv: isopropanol (67-63-0))
Boiling point 427.5±48.0 °C(Predicted)
density 1.29±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Chloroform (Sparingly), Methanol (Slightly)
form Solid
pka3.15±0.30(Predicted)
color White to Off-White
CAS DataBase Reference99010-64-7(CAS DataBase Reference)
Safety Information
HS Code 2934990002
MSDS Information
4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline Usage And Synthesis
Description4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline is a chemical product that has been used as a photosynthetic activator in weed science and pest control. It has been shown to significantly increase the growth rate of wheat, soybean, and oilseed crops. It is also effective at controlling weeds by inhibiting their ability to produce chlorophyll, thereby preventing them from photosynthesizing. 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline has also been shown to be an effective herbicide for agricultural use.
UsesDesamino Chloroimiquimod (Imiquimod USP Related Compound C) is a pharmacologically active compound related to Imiquimod (I475000), an immune response modifier. It stimulates the production of Interferon-a.
Synthesis4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline is prepared by the reaction of 2-chloro-N4-(2-methylpropyl)quinoline-3,4-diamine and orthoformic acid triethyl ester. The specific synthesis steps are as follows:
A suspension of 2-chloro-N4 -(2-methylpropyl)-3,4-quinolinediamine (35 g) and triethylorthoformate (52.3 g, 2.5 eq) was heated at 145° C. for 10 h, during which time ethanol was removed by distillation. The resulting mixture was cooled to room temperature and the solid was removed by filtration. The solid was dissolved in hydrochloric acid (100 mL, 4N). The resulting solution was added to a solution of sodium hydroxide. The precipitate was filtered and washed with water to afford the product 4-chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline in 92% yield.
4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline synthesis
4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline Preparation Products And Raw materials
Tag:4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline(99010-64-7) Related Product Information
4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol [99010-09-0], C13H17N3,215.30 Imiquimod Related Compound B (25 mg) (1-Isobutyl-1H-imidazo[4,5-c]quinoline 5-oxide) Imiquimod Related Compound D (25 mg) (1-Propyl-1H-imidazo[4,5-c]quinolin-4-amine) Imiquimod Chloromethyl isopropyl carbonate Epichlorohydrin 1-Methylimidazole 3-Methyl-2-butanone Imiquimod Impurity 2 Imiquimod Impurity 6 Imiquimod Impurity 5 1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINE Difluorochloromethane Chloroacetic acid RESIQUIMOD 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline 4-CHLORO-1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINE 98%MIN