胰高血糖素稳定类似物多肽DASIGLUCAGON 基本信息
| 中文名称 | 胰高血糖素稳定类似物多肽DASIGLUCAGON |
|---|---|
| 中文同义词 | 胰高血糖素稳定类似物多肽DASIGLUCAGON;达西格列酮 |
| 英文名称 | L-Threonine, L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-α-aspartyl-2-methylalanyl-L-alanyl-L-arginyl-L-alanyl-L-α-glutamyl-L-α-glutamyl-L-phenylalanyl-L-valyl-L-lysyl-L-tryptophyl-L-leucyl-L-α-glutamyl-L-seryl- |
| 英文同义词 | L-Threonine, L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-α-aspartyl-2-methylalanyl-L-alanyl-L-arginyl-L-alanyl-L-α-glutamyl-L-α-glutamyl-L-phenylalanyl-L-va;Dasiglucagon;L-Threonine, L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-α-as;L-Threonine, L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-α-aspartyl-2-methylalanyl-L-alanyl-L-arginyl-L-alanyl-L-α-glutamyl-L-α-glutamyl-L-phenylalanyl-L-valyl-L-lysyl-L-tryptophyl-L-leucyl-L-α-glutamyl-L-seryl-;L-Threonine, L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-α-aspartyl-2-methylalanyl-L-alanyl-L-arginyl-L-alanyl-L-α-glutamyl-L-α-glutamyl-L-phenylalanyl-L-valyl-L-lysyl-L-tryptophyl-L-leucyl-L-α-glutamy...;Contezolid Impurity 7 |
| CAS号 | 1544300-84-6 |
| 分子式 | C152H222N38O50 |
| 分子量 | 3381.66 |
| EINECS号 | |
| 相关类别 | 小分子抑制剂;医药原料;贝尔卡主打;武汉贝尔卡主打 |
| Mol文件 | 1544300-84-6.mol |
| 结构式 |  |
胰高血糖素稳定类似物多肽DASIGLUCAGON 性质
| 密度 | 1.50±0.1 g/cm3(Predicted) |
|---|---|
| 序列 | H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Aib-Ala-Arg-Ala-Glu-Glu-Phe-Val-Lys-Trp-Leu-Glu-Ser-Thr-OH |
多肽
胰高血糖素稳定类似物多肽Dasiglucagon是一种全球首创的胰高血糖素稳定类似物多肽。与活性对照药物相比，对于胰岛素引起的低血糖症状，Dasiglucagon可迅速升高其血糖水平，血糖升高持续时间更长，效果也更明显。同时Dasiglucagon治疗糖尿病严重低血糖的儿科III期临床研究的积极结果。参考质量标准
外观:白色粉末纯度(HPLC) ≥98.0%
醋酸根含量≤12.0%
水分含量≤8.0%
肽含量≥80.0%
内毒素≤50EU/mg
氨基酸组成分析≤±10%