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Procaine hydrochloride

Procaine hydrochloride Suppliers list
Company Name: Shanghai Bojing Chemical Co.,Ltd.
Tel: +86-21-37122233
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Products Intro: Product Name:procaine HCL
CAS:51-05-8
Purity:99% Package:1Kg;25kg/ Drum or as customer request
Company Name: Shenzhen Sendi Biotechnology Co.Ltd.
Tel: 0755-23311925 18102838259
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Products Intro: Product Name:Procaine hydrochloride
CAS:51-05-8
Purity:99% Package:77/KG
Company Name: Alfa Aesar  Gold
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Products Intro:Product Name:2-DiethylaMinoethyl 4-aMinobenzoate hydrochloride, 99%
CAS:51-05-8
Package:50g Remarks:A17485
Company Name: Shenzhen Sendi Biological Technology Co., Ltd.  Gold
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Products Intro:Product Name:Procaine hydrochloride
CAS:51-05-8
Purity:99% Package:77/KG 25KG
Company Name: Wuhan Magic Biological Technology Co., Ltd.  Gold
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Products Intro:Product Name:Procaine Hydrochloride
CAS:51-05-8
Package:1KG,25KG
Procaine hydrochloride Basic information
Local anesthetic
Product Name:Procaine hydrochloride
Synonyms:aminocaine;anadolor;anesthesol;anestil;atoxicocaine;Benzoicacid,4-amino-,2-(diethylamino)ethylester,monohydrochloride;benzoicacid,p-amino-,2-(diethylamino)ethylester,monohydrochloride;bernocaine
CAS:51-05-8
MF:C13H21ClN2O2
MW:272.77
EINECS:200-077-2
Product Categories:Pharmaceutical;Sodium channel;APIS;Anesthetics;Pharmaceutical intermediate
Mol File:51-05-8.mol
Procaine hydrochloride Structure
Procaine hydrochloride Chemical Properties
Melting point 155-156 °C(lit.)
Boiling point 195-196°C 17mm
Fp 195-196°C/17mm
storage temp. room temp
form Crystals or Crystalline Powder
color Colorless to white
Water Solubility soluble
Sensitive Air Sensitive
Merck 14,7757
Stability:Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference51-05-8(CAS DataBase Reference)
EPA Substance Registry SystemBenzoic acid, 4-amino-, 2-(diethylamino)ethyl ester, monohydrochloride(51-05-8)
Safety Information
Hazard Codes T
Risk Statements 25-43-36/37/38-23/24/25
Safety Statements 36/37/39-45-37/39-26
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS DG2275000
TSCA Yes
HazardClass 6.1
PackingGroup III
MSDS Information
ProviderLanguage
Procaine hydrochloride English
SigmaAldrich English
ACROS English
ALFA English
Procaine hydrochloride Usage And Synthesis
Local anestheticProcaine hydrochloride is a topical anesthetic, which can block the nerve fiber conduction temporarilyand has a narcotic effect,strong effect, low toxicity, and non-addictive, but on the skin, mucosal penetration is weak, unsuitable for surface anesthesia, patients are used for infiltration, conduction and spinal anesthesia.
White fine needle crystal or crystalline powder at room temperature, no smell, taste slightly bitter and Ma, soluble in water, soluble in ethanol, slightly soluble in chloroform, almost insoluble in ether. Procaine hydrochloride ester bond structure can be hydrolyzed to produce amino acid and diethylaminoethanol, under certain conditions, the amino acid may be further decarboxylated toxic aniline.
The structure of procaine hydrochloride with aromatic primary amino, easy oxidation discoloration pH, temperature, UV, oxygen and metal ions can accelerate the oxidation discoloration. The aqueous solution was stable in pH3.0~5. So preparation of procaine hydrochloride injection, it generally takes add acid to regulate pH 3.3 to 5.5, and strictly control the sterilization temperature and time. to 100 ℃ steam sterilization 30min circulation is appropriate, and should pay attention to shading, sealed save.
The product structure of aromatic primary amino group in dilute hydrochloric acid can generate diazonium salt with sodium nitrite, coupling reaction occurs when add alkaline β-naphthol, generating azo compounds scarlet.
The above information is edited by the chemicalbook of Kui Xiongfeng.
Chemical Propertieswhite crystalline powder
UsesLocal anesthesic;Na+ channel blocker
UsesProcaine is a local anesthetic of the amino ester group that is primarily used as a topical anesthetic. Procaine is also used to control the pain of intramuscular injection of penicillin as well as in dentistry.
UsesNon Caine local anesthetic.
UsesA sodium channel blocker and DNA methylation inhibitor
Procaine hydrochloride Preparation Products And Raw materials
Preparation ProductsProcaine penicillin G
Raw materialsDiethylamine-->p-Nitrobenzoic acid
Tag:Procaine hydrochloride(51-05-8) Related Product Information
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