2,3,5-Trifluoropyridine manufacturers
- 2,3,5-Trifluoropyridine
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- $21.00 / 1KG
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2024-04-17
- CAS:76469-41-5
- Min. Order: 1KG
- Purity: 99.0% min
- Supply Ability: 100 tons
- 2,3,5-Trifluoropyridine
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- $1.10 / 1g
-
2024-04-17
- CAS:76469-41-5
- Min. Order: 1g
- Purity: 99.0% min
- Supply Ability: 100 tons min
- 2,3,5-Trifluoropyridine
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- $1.10 / 1g
-
2021-10-19
- CAS:76469-41-5
- Min. Order: 1g
- Purity: 99.00%
- Supply Ability: 100 Tons Min
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| | 2,3,5-Trifluoropyridine Basic information | | Synthesis |
| Product Name: | 2,3,5-Trifluoropyridine | | Synonyms: | 2,3,5-TRIFLUOROPYRIDINE;2,3,5-Trifluoropyridine 98%;2,3,5-Trifluoropyridine98%;Pyridine, 2,3,5-trifluoro-;2,3,5-Trifluoropyridine ISO 9001：2015 REACH | | CAS: | 76469-41-5 | | MF: | C5H2F3N | | MW: | 133.07 | | EINECS: | 680-886-9 | | Product Categories: | Fluorine series;Pyridine;bc0001 | | Mol File: | 76469-41-5.mol |  |
| | 2,3,5-Trifluoropyridine Chemical Properties |
| Boiling point | 102°C | | density | 1,499 g/cm3 | | refractive index | 1.422 | | Fp | 30°C | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | form | clear liquid | | pka | -5.28±0.20(Predicted) | | color | Colorless to Light yellow | | Specific Gravity | 1.499 | | Water Solubility | Difficult to mix in water. | | BRN | 6385503 | | CAS DataBase Reference | 76469-41-5(CAS DataBase Reference) |
| Hazard Codes | Xi,F,C | | Risk Statements | 36/37/38-10 | | Safety Statements | 26-36/37/39-37 | | RIDADR | 1993 | | Hazard Note | Flammable/Irritant | | HazardClass | 3 | | PackingGroup | III | | HS Code | 29333990 |
| | 2,3,5-Trifluoropyridine Usage And Synthesis |
| Synthesis | A solution of pentafluoropyridine (3) (0.6 g, 3.6 mmol) in tetrahydrofuran (5 cm3) was added to a mixture of lithium aluminium hydride (5 cm3, 5 mmol of 1.0 M solution in ether) and 12-crown-4 (1.0 g, 5.7 mmol) in THF (10 cm3) at 0 "C, with stirring, under an atmosphere of dry nitrogen. The mixture was stirred at 0 "C for 10 min, then at room temperature for 19 h, then iced water added and the mixture extracted into ether. The ether solution was dried (MgS04), evaporated and the products were isolated by preparative scale GLC (1 0% SE, 40"C), giving 2,3,5-trifluoropyridine (7, 92%) 50(Found: C, 44.9; H, 1.3; N, 10.5. Calc. for C5H2F3N: C, 45.1; H, 1.5; N, 10.5); IR spectrum no. 2; mass spectrum no. 3; nmr spectrum no. 3. | | Chemical Properties | Colorless liquid | | Uses | It is employed as a pharmaceutical intermediate. |
| | 2,3,5-Trifluoropyridine Preparation Products And Raw materials |
| Preparation Products | 2,5-Difluoropyridine-->3,4,5-Trifluoropyridine-->2,3,6-TRIFLUOROPYRIDINE-->2,3,4,5-Tetrafluoropyridine-->4-Bromo-2,3,5-trifluoropyridine |
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