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1,4-Dimethoxybenzene

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1,4-Dimethoxybenzene Basic information
Product Name:1,4-Dimethoxybenzene
Synonyms:2-Benzimidazolinone, 1,3-bis(hydroxymethyl)-;Anisole, p-methoxy-;Benzene, p-dimethoxy-;Benzene,1,4-dimethoxy-;Dimethyl ether hydroquinone;QUINOL DIMETHYL ETHER;FEMA 2386;1,4-DIMETHOXYBENZENE
CAS:150-78-7
MF:C8H10O2
MW:138.16
EINECS:205-771-9
Product Categories:Organic Building Blocks;Oxygen Compounds;Benzene derivates;Aromatic Ethers;Building Blocks;C2 to C8;Chemical Synthesis;Ethers;150-78-7
Mol File:150-78-7.mol
1,4-Dimethoxybenzene Structure
1,4-Dimethoxybenzene Chemical Properties
Melting point 54-56 °C(lit.)
Boiling point 213 °C(lit.)
density 1.053 g/mL at 25 °C(lit.)
vapor density 4.8 (vs air)
vapor pressure <1 mm Hg ( 20 °C)
refractive index 1.5231 (estimate)
FEMA 2386 | P-DIMETHOXYBENZENE
Fp 98 °C
storage temp. Sealed in dry,Room Temperature
solubility dioxane: 0.1 g/mL, clear
form Crystalline Powder, Crystals, or Flakes
color White
Specific Gravity1.053
PH7 (H2O, 20℃)(saturated solution)
Odorat 1.00 % in dipropylene glycol. sweet green new mown hay fennel
Odor Typegreen
explosive limit1.2-5.6%(V)
Water Solubility 0.8 g/l (20 ºC)
Sensitive Light Sensitive
JECFA Number1250
BRN 774605
Dielectric constant4.5(23℃)
Stability:Stable. Combustible. Incompatible with strong oxidizing agents.
LogP2.08 at 20℃
CAS DataBase Reference150-78-7(CAS DataBase Reference)
NIST Chemistry ReferenceBenzene, 1,4-dimethoxy-(150-78-7)
EPA Substance Registry Systemp-Dimethoxybenzene (150-78-7)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-24/25
WGK Germany 1
RTECS CZ6650000
Autoignition Temperature1463 °F
TSCA Yes
HS Code 29093090
Hazardous Substances Data150-78-7(Hazardous Substances Data)
MSDS Information
ProviderLanguage
1,4-Dimethoxybenzene English
SigmaAldrich English
ACROS English
ALFA English
1,4-Dimethoxybenzene Usage And Synthesis
Chemical Propertiesp-Dimethoxybenzene has a bitter taste.
Chemical PropertiesHydroquinone Dimethyl Ether occurs in hyacinth oil and has also been identified in tea. It is a white, crystalline solid (mp 57–58°C) with an intensely sweet, somewhat herbal, nut-like odor.
Hydroquinone dimethyl ether is prepared by etherification of hydroquinone and is used in soap perfumes.
Chemical Propertieswhite crystals or powder
OccurrenceReported found in hyacinth (Hyacinthus orientalis L.) essential oil, Rhodophyllus icterius, papaya, peppermint oil, green tea, cherimoya and cooked shrimp
UsesWeathering agent in paints and plastics, fixative in perfumes, dyes, resin intermediate, cosmetics, especially suntan preparations, flavoring.
Uses1,4-Dimethoxybenzene is used as Pharmaceutical Intermediate. It is used in some paints and as a diazo dye. It is also used in perfumes and flavors in order to its floral odor. In addition, it is used on greasy skin, and with sulfur to treat acne, or as a dandruff treatment.
PreparationBy methylation of hydroquinone using dimethyl sulfate and alkali.
DefinitionChEBI: 1,4-Dimethoxybenzene is a dimethoxybenzene.
Synthesis Reference(s)Journal of the American Chemical Society, 83, p. 1251, 1961 DOI: 10.1021/ja01466a056
General DescriptionColorless crystals.
Air & Water ReactionsSlightly water soluble .
Reactivity Profile1,4-Dimethoxybenzene is an ether. Ethers may react violently with strong oxidizing agents. In other reactions, which typically involve the breaking of the carbon-oxygen bond, ethers are relatively inert.
Flammability and ExplosibilityNot classified
Purification MethodsSteam distil 1,4-dimethoxybenzene, then crystallise it from hexane or *benzene, and from MeOH or EtOH, but these are wasteful due to high solubilities. Dry it under vacuum. It also sublimes under vacuum. [Beilstein 6 IV 5718.]
Tag:1,4-Dimethoxybenzene(150-78-7) Related Product Information
Dimethyl sulfoxide Dacthal ETHANE Hydroquinone Hydroquinone bis(2-hydroxyethyl)ether 1,2-Dimethoxyethane 1,1-Dimethoxyethane tert-Butylhydroquinone Dimethyl carbonate 4-Methoxyphenol 1,4-Diacetoxybenzene 4-Dimethylaminobenzaldehyde Dimethyl fumarate Dimethyldimethoxysilane Terephthaloyl chloride N,N-Dimethylformamide 1,4-Bis(methoxymethyl)benzene Terephthalic acid Hydroquinone Dimethyl Ether