Log in | Join Free | china | japan | germany
ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >Silane >N-(Trimethylsilyl)acetamide

N-(Trimethylsilyl)acetamide

Request For Quotation
N-(Trimethylsilyl)acetamide Suppliers list
Company Name: Shanghai Daken Advanced Materials Co.,Ltd
Tel: +86-371-66670886
Email: info@dakenam.com
Products Intro: Product Name:DK063
CAS:13435-12-6
Purity:99% Package:1KG ;10KG ;100KG Remarks:Low M.W.Organic Silanes Professor
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: +86-0371-55170693 +86-19937530512
Email: info@tianfuchem.com
Products Intro: Product Name:13435-12-6 N-(Trimethylsilyl)acetamide
CAS:13435-12-6
Purity:99% Package:25KG;5KG;1KG
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:N-(trimethylsilyl)acetamide
CAS:13435-12-6
Purity:98% HPLC Package:5G;10G;25G;50G;100G;250G;1KG
Company Name: Win-Win Chemical CO., Limited
Tel: 0086-577-64498589
Email: sales@win-winchemical.com
Products Intro: Product Name:N-(trimethylsilyl)acetamide
CAS:13435-12-6
Purity:98% Package:10G/ Remarks:pharmaceutical intermediates
Company Name: Chongqing Chemdad Co., Ltd
Tel: +86-023-61398051 +8613650506873
Email: sales@chemdad.com
Products Intro: Product Name:N-(Trimethylsilyl)acetamide
CAS:13435-12-6
Package:1kg，2kg，5kg，10kg，25kg

N-(Trimethylsilyl)acetamide manufacturers

  • N-(Trimethylsilyl)acetamide
  • N-(Trimethylsilyl)acetamide pictures
  • $15.00 / 1KG
  • 2021-07-13
  • CAS:13435-12-6
  • Min. Order: 1KG
  • Purity: 99%+ HPLC
  • Supply Ability: Monthly supply of 1 ton
  • N-(Trimethylsilyl)acetamide
  • N-(Trimethylsilyl)acetamide pictures
  • $15.00 / 1KG
  • 2021-07-10
  • CAS:13435-12-6
  • Min. Order: 1KG
  • Purity: 99%+ HPLC
  • Supply Ability: Monthly supply of 1 ton
N-(Trimethylsilyl)acetamide Basic information
Product Name:N-(Trimethylsilyl)acetamide
Synonyms:N-(TRIMETHYLSILYL)ACETAMIDE FOR SYNTHESI;N-(Trimethylsilyl)acetamide,97%;N-(Trimethylsilyl);(acetylamino)trimethylsilane;n-(trimethylsilyl)-acetamid;N-TRIMETHYLSILYLACETAMIDE;TRIMETHYLSILYLACETAMIDE;TMSA
CAS:13435-12-6
MF:C5H13NOSi
MW:131.25
EINECS:236-565-7
Product Categories:Aliphatics;Miscellaneous Reagents;Analytical Chemistry;GC Derivatizing Reagents;Si (Classes of Silicon Compounds);Silicon Compounds (for Synthesis);Silylacetamides;Silylation (GC Derivatizing Reagents);Si-N Compounds;Synthetic Organic Chemistry;Trimethylsilylation (GC Derivatizing Reagents)
Mol File:13435-12-6.mol
N-(Trimethylsilyl)acetamide Structure
N-(Trimethylsilyl)acetamide Chemical Properties
Melting point 46-49 °C(lit.)
Boiling point 84 °C18 mm Hg(lit.)
density 0.859±0.06 g/cm3(Predicted)
Fp 135 °F
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform, DMSO, Methanol
pka18.23±0.46(Predicted)
form Crystalline Mass
color White to yellow
Water Solubility reacts
Sensitive Moisture Sensitive
Hydrolytic Sensitivity7: reacts slowly with moisture/water
BRN 741928
Stability:Moisture Sensitive
CAS DataBase Reference13435-12-6(CAS DataBase Reference)
EPA Substance Registry SystemAcetamide, N-(trimethylsilyl)- (13435-12-6)
Safety Information
Hazard Codes Xi-F,Xi,F
Risk Statements 36/37/38-11
Safety Statements 37/39-26
RIDADR 1325
WGK Germany 3
RTECS AD0250000
F 10-21
TSCA Yes
HazardClass 4.1
PackingGroup III
HS Code 29319090
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
N-(Trimethylsilyl)acetamide Usage And Synthesis
Chemical PropertiesWHITE TO YELLOWISH CRYSTALLINE MASS
UsesN-Trimethylsilylacetamide is a silylating agent used in organic synthesis. N-Trimethylsilylacetamide is used in the preparation of the antibacterial agent Cefdinir (C242670).
General DescriptionThe efficiency of N-(Trimethylsilyl)acetamide (TMS acetamide) as allyl group scavenger and its compatibility with Fluorenylmethyloxycarbonyl chloride (Fmoc) protecting groups were studied.
Purification MethodsDistil the amide repeatedly in an inert atmosphere with all operations to be performed in an anhydrous atmosphere. In the presence of moisture, trimethylsilanol (b 31-34o/26mm) is formed and is a likely impurity (check by NMR). [Birkofer et al. Chem Ber 96 1473 1963, Beilstein 4 IV 4011.]
N-(Trimethylsilyl)acetamide Preparation Products And Raw materials
Preparation ProductsCefdinir-->2-METHYL-1-(TRIMETHYLSILOXY)-1-PROPENE-->1-(Trimethylsiloxy)cyclopentene-->Allylisopropylacetamide
Tag:N-(Trimethylsilyl)acetamide(13435-12-6) Related Product Information
N,N-Dimethylacetamide Acetamide Trimethylsilylacetylene Acetaminophen 1-TRIMETHYLSILYL-2-PYRROLIDINONE N,O-Bis(trimethylsilyl)acetamide Silicone rubber,methyl-vinyl N-(tert-Butyldimethylsilyl)-N-methyl-trifluoroacetamide BIS(TRIMETHYLSILYL)HYPOXATHINE N-METHYL-N-TRIMETHYLSILYLHEPTAFLUOROBUTYRAMIDE N-Methyl-N-(trimethylsilyl)acetamide N-Methyl-N-(trimethylsilyl)trifluoroacetamide N-(TERT-BUTYLDIMETHYLSILYL)PHTHALIMIDE N,N-Bis(trimethylsilyl)acetamide (4S)-N-(TERT-BUTYLDIMETHYLSILYL)AZETIDIN-2-ONE-4-CARBOXYLIC ACID (4R)-N-(TERT-BUTYLDIMETHYLSILYL)AZETIDIN-2-ONE-4-CARBOXYLIC ACID (5-METHYL-1,3-BIS-TRIMETHYLSILYL)-2,4-(1H,3H-PYRIMIDINEDIONE) METHACRYLAMIDOTRIMETHYLSILANE