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1,5-Diaminopentane

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CAS:462-94-2
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  • Purity: 99%
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  • Purity: 99.%
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1,5-Diaminopentane Basic information
Product Name:1,5-Diaminopentane
Synonyms:Animal coniine;animalconiine;H2N(CH2)5NH2;5,5'-PENTANEDIAMINE;1,5-DIAMINOPENTANE;CADAVERIN FREE BASE extrapure;1,5-Diaminopentane, 1,5-Pentanediamine, Pentamethylenediamine;CADAVERINE, APPROX. 98%
CAS:462-94-2
MF:C5H14N2
MW:102.18
EINECS:207-329-0
Product Categories:Building Blocks;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks;Polyamines;Amines;alpha,omega-Alkanediamines;alpha,omega-Bifunctional Alkanes;Monofunctional & alpha,omega-Bifunctional Alkanes
Mol File:462-94-2.mol
1,5-Diaminopentane Structure
1,5-Diaminopentane Chemical Properties
Melting point 9 °C
Boiling point 178-180 °C(lit.)
density 0.873 g/mL at 25 °C(lit.)
vapor pressure 1.29-17hPa at 20-25℃
refractive index n20/D 1.458(lit.)
Fp 145 °F
solubility 1 M HCl: soluble0.5g/10 mL, clear, colorless
pka10.05(at 25℃)
form Liquid
color Clear colorless to yellow
Odorcharacteristic odor
Water Solubility soluble
Sensitive Air Sensitive & Hygroscopic
Merck 14,1609
BRN 1697256
Stability:Stable. Incompatible with acid chlorides, acids, acid anhydrides, strong oxidizing agents, carbon dioxide.
InChIKeyVHRGRCVQAFMJIZ-UHFFFAOYSA-N
LogP-0.3--0.15 at 21℃
CAS DataBase Reference462-94-2(CAS DataBase Reference)
NIST Chemistry Reference1,5-Diaminopentane(462-94-2)
EPA Substance Registry SystemCadaverine (462-94-2)
Safety Information
Hazard Codes C
Risk Statements 34-36/37
Safety Statements 26-36/37/39-45-25-27
RIDADR UN 2735 8/PG 3
WGK Germany 3
RTECS SA0200000
10
HazardClass 8
PackingGroup III
HS Code 29212900
Hazardous Substances Data462-94-2(Hazardous Substances Data)
Toxicitydni-mus:ast 10 mmol/L AMOKAG 33,149,79
MSDS Information
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1,5-Diaminopentane Usage And Synthesis
Chemical Propertiescolourless to light yellow liquid with a very unpleasant smell
UsesCadaverine is a diamine that can be used in hetarylation with halopyridines (2-bromo, 2-iodo, and 3-iodo-pyridines) to synthesize N,N′-dipyridinyl diamine derivatives in the presence of CuI-2-isobutyrylcyclohexanone as a catalyst. It can also be used to synthesize a poly-imidazolium polymer with high thermal stability by reacting with acetic acid, pyruvaldehyde and formaldehyde by modified Debus-Radziszewski reaction.
Uses1,5-Diaminopentane is mainly used in organic synthesis.
DefinitionChEBI: An alkane-alpha,omega-diamine comprising a straight-chain pentane core with amino substitutents at positions 1 and 5. A colourless syrupy liquid diamine with a distinctive unpleasant odour, it is a homologue of putresceine and is formed by the bacterial decarboxylation of lysine that occurs during protein hydrolysis during putrefaction of animal tissue. It is also found in plants such as soyabean.
Production Methods1,5-Diaminopentane can be prepared by methods similar to those described for 1,4-diaminobutane. The starting materials are 1,5-dichloropentane (obtainable from tetrahydropyran), glutarodinitrile, or glutaraldehyde. The compound is hygroscopic and has a very bad odor.
General DescriptionCadaverine, a biogenic amine, belongs to the class of aliphatic diamines and is commonly found in food products including cheese, fish products, fermented sausages, fish sauces, etc. It can be used as a freshness marker and as an indicator of microbial spoilage since it is most commonly identified in food products as a result of inappropriate storage conditions and microbial contamination.
Flammability and ExplosibilityNot classified
Safety ProfilePoison by intravenous, rectal, and subcutaneous routes. Moderately toxic by skin contact. An irritant, sensitizer, and allergen. Mutagenic data. When heated to decomposition it emits highly toxic fumes of NOx.
Purification MethodsPurify the base by distillation, after standing over KOH pellets (at room temperature, i.e. liquid form). Its dihydrochloride has m 275o (sublimes in a vacuum), and its tetraphenyl boronate has m 164o. [Schwarzenbach et al. Helv Chim Acta 35 2333 1952, Beilstein 4 IV 1310.]
Tag:1,5-Diaminopentane(462-94-2) Related Product Information
N,N-Dimethyl-1,4-phenylenediamine 1,5-Pentanediol p-Phenylenediamine Iminodiacetic acid 4,4'-Methylenedianiline 2,3-DIAMINOTOLUENE 4,4'-Diaminodiphenylsulfone Amylamine TRIAMYLAMINE Diethylenetriamine Iminodiacetonitrile Glutaraldehyde Diethanolamine HEXANES 2-(Aminomethyl)-1-ethylpyrrolidine 2-METHYL-1,5-DIAMINOPENTANE DIANTIPYRYLMETHANE STRYCHNINE