| Company Name: |
Nantong Hi-Future Biotechnology Co., Ltd
|
| Tel: |
18051384581 |
| Email: |
sales@chemhifuture.com |
| Products Intro: |
Product Name:ethiazide
CAS:1824-58-4
Purity:98% HPLC Package:10mg，500mg，1g，5g，10g，more
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:Ethiazide;Ethiazide
CAS:1824-58-4
Purity:98% Package:5 mg
|
|
| | ethiazide Basic information |
| Product Name: | ethiazide | | Synonyms: | 6-Chloro-3-ethyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide;Eclotizide;Etizide;Neo Diuresal;Salta;6-chloro-3-ethyl-1,1-diketo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide;6-chloro-3-ethyl-1,1-dioxo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide;ethiazide | | CAS: | 1824-58-4 | | MF: | C9H12ClN3O4S2 | | MW: | 325.79 | | EINECS: | 217-358-0 | | Product Categories: | | | Mol File: | 1824-58-4.mol |  |
| | ethiazide Chemical Properties |
| Melting point | 269-270° | | Boiling point | 563.5±60.0 °C(Predicted) | | density | 1.526±0.06 g/cm3(Predicted) | | pka | 9.01±0.40(Predicted) |
| | ethiazide Usage And Synthesis |
| Originator | Ethiazide,Tokyo Tanabe,Japan,1970 | | Definition | ChEBI: Ethiazide is a benzothiadiazine. | | Manufacturing Process | A mixture of 2.9 grams of 5-chloro-2,4-disulfamyl-aniline in 20 ml of
anhydrous diethylene glycoldimethylether, 0.44 gram of propionaldehyde and
0.5 ml of a solution of hydrogen chloride in ethyl acetate (109.5 grams
hydrogen chloride per 1,000 ml) is heated to 80° to 90°C and maintained at
that temperature for 1 hour. The reaction mixture is concentrated under
reduced pressure; on addition of water, the product separates and is then
recrystallized from ethanol or aqueous ethanol to yield the desired 6-chloro-3-
ethyl-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide, MP 269° to
270°C. | | Therapeutic Function | Diuretic, Cardiotonic, Smooth muscle relaxant,
Respiratory stimulant |
| | ethiazide Preparation Products And Raw materials |
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