- 4-methylquinoline
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- $0.00 / 25KG
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2023-08-26
- CAS:491-35-0
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 50000KG/month
- 4-Methylquinoline
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- $0.00 / 1KG
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2023-01-19
- CAS:491-35-0
- Min. Order: 1KG
- Purity: 98%min
- Supply Ability: 30tons/month
- Lepidine
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- $1.10 / 1g
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2022-03-04
- CAS:491-35-0
- Min. Order: 1g
- Purity: 99.00%
- Supply Ability: 100 Tons
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| 4-methylquinoline Basic information |
| 4-methylquinoline Chemical Properties |
Melting point | 9-10 °C(lit.) | Boiling point | 261-263 °C(lit.) | density | 1.083 g/mL at 25 °C(lit.) | refractive index | n20/D 1.620(lit.) | Fp | >230 °F | storage temp. | Refrigerator | solubility | Chloroform (Slightly), Methanol (Slightly) | pka | 5.67(at 20℃) | form | Liquid | color | Pale Orange | Odor | at 100.00 %. burnt oily herbal floral sweet | Odor Type | burnt | Water Solubility | Slightly soluble | Sensitive | Light Sensitive | Merck | 14,5441 | BRN | 110926 | InChIKey | MUDSDYNRBDKLGK-UHFFFAOYSA-N | LogP | 2.610 | CAS DataBase Reference | 491-35-0(CAS DataBase Reference) | NIST Chemistry Reference | Quinoline, 4-methyl-(491-35-0) | EPA Substance Registry System | Quinoline, 4-methyl- (491-35-0) |
| 4-methylquinoline Usage And Synthesis |
Description | Refer to 6-METHYLQUINOLINE. | Chemical Properties | clear slightly yellow to brown liquid | Physical properties | 4-Methylquinoline is a colorless liquid with a weak quinoline-like odor. It is slightly soluble in water, miscible with many organic solvents, and volatile in steam. | Uses | Lepidine is used in the preparation of certain dyes. | Uses | 4-Methylquinoline is used as a reagent in the synthesis of azetidine based ene-amides as potent bacterial enoyl ACP reductase inhibitors. Also used as a reagent in the synthesis of cyanine-styryl dyes with enhanced photostability for fluorescent DNA imaging. | Definition | ChEBI: A methylquinoline carrying a methyl substituent at position 4. | Production Methods | 4-Methylquinoline can be recovered from the highest-boiling fraction of the coal-tar quinoline bases via its o-cresol addition compound. It can be synthesized by condensation of aniline and methyl vinyl ketone. | Synthesis Reference(s) | Tetrahedron Letters, 28, p. 5291, 1987 DOI: 10.1016/S0040-4039(00)96710-8 | General Description | Synthesis of lepidine from 4-anilinobutan-2-one in ethanol in the presence of HCl or FeCl3 has been reported. Nitration of lepidine has been reported. | Purification Methods | Reflux lepidine with BaO, then fractionally distil it. Further purify it via its recrystallised dichromate salt (m 138o) (from H2O). [Cumper et al. J Chem Soc 1176 1962.] [Beilstein 20 III/IV 3477, 20/7 V 389.] |
| 4-methylquinoline Preparation Products And Raw materials |
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