表油菜素内酯
| 中文名称 | 表油菜素内酯 |
|---|---|
| 中文同义词 | 布拉西诺内酯;表油菜素内酯;欧洲油菜素;BRASSINOLIDE 24-表油菜素内酯;(22R,23R,24R)-2Α,3Α,22,23-四羟基-Β-高-7-氧杂-5Α-麦角甾-6-酮;芸苔素内酯/表油菜素内酯;24-表芸苔素内酯;(22R,23R,24R)-2Α,3Α,22,23-四羟基-24-甲基-5Α-胆甾-6-酮 |
| 英文名称 | Epibrassinolide |
| 英文同义词 | 22R,23R,24R-2ALPHA,3ALPHA,22,28-TETRAHYDROXY-B-HOMO-7-OXA-5ALPHA-ERGOSTA-6-ONE;(22R,23R,24R)-2-ALPHA,3-ALPHA,22,23-TETRAHYDROXY-24-METHYL-B-HOMO-7-OXA-5-ALPHA-CHOLESTAN-6-ONE;22R,23R,24R-2A,3A,22,23-TETRAHYDROXY-B-HOMO-7-OXA-5A-ERGOSTAN-6-ONE;24R-BRASSINOLIDE;2-ALPHA,3-ALPHA,22R,23R,-TETRAHYDROXY-B-HOMO-7-OXA-5-ALPHA-ERGOSTAN-6-ONE;2-ALPHA,3-ALPHA,22R,23R-TETRADHYDROXY-24R-METHYL-B-HOMO-7-OXA-5-ALPHA-CHOLESTAN-6-ONE;5-ALPHA-CHOLESTANE-B-HOMO-7-OXA-24-BETA-METHYL-2-ALPHA, 3-ALPHA, 22-ALPHA, 23-ALPHA-TETROL-6-ONE;EPIBRASSINOLIDE 98% (HPLC) |
| CAS号 | 78821-43-9 |
| 分子式 | C28H48O6 |
| 分子量 | 480.68 |
| EINECS号 | 639-387-1 |
| 相关类别 | 生物活性小分子;植物生长调节剂;化肥与农药;植物激素及核酸类;新品推荐;医药原料药-科研原料;农资类产品;生化试剂-植物激素及核酸类;农药中间体;农用;农药原料;原料;原料药;科研-18271818137;通用生化试剂-植物激素;Steroids;Bio-Pesticide;Steroids & Hormones - 13C & 2H;PLANT GROWTH REGULATOR;Intermediates & Fine Chemicals;Pharmaceuticals;Steriod;中间体-农药中间体;对照品;其他 |
| Mol文件 | 78821-43-9.mol |
| 结构式 |  |
表油菜素内酯 性质
| 熔点 | 256°C |
|---|---|
| 沸点 | 633.7±55.0 °C(Predicted) |
| 密度 | 1.141±0.06 g/cm3(Predicted) |
| 储存条件 | -20°C |
| 溶解度 | 氯仿（微溶）、乙酸乙酯（微溶） |
| 形态 | 固体 |
| 酸度系数(pKa) | 14.27±0.70(Predicted) |
| 颜色 | 白色至类白色 |
| EPA化学物质信息 | 3H-Benz[c]indeno[5,4-e]oxepin-3-one, 10-[(1S,2R,3R,4R)-2,3-dihydroxy-1,4,5-trimethylhexyl]hexadecahydro-5,6-dihydroxy-7a,9a-dimethyl-, (3aS,5S,6R,7aR,7bS,9aS,10R,12aS,12bS)- (78821-43-9) |
Plant growth regulator, Apoptosis inducer
Epibrassinolide (EBR) is a biologically active compound of the brassinosteroids, steroid-derived plant growth regulator family. Cells are incubated with various doses (0-100 μM) of Epibrassinolide for 24 or 48 h and cell viability is determined by MTT assay. Epibrassinolide induced cell viability loss in dose- and time-dependent manner compared to untreated samples in LNCaP and DU145 prostate cancer cells. Increasing concentrations of Epibrassinolide is more effective on LNCaP cell viability loss than DU145 cells suggesting that androgen-dependent cells are more sensitive to Epibrassinolide than androgen-independent prostate cancer cells. In further experiments, 25 μM Epibrassinolide is selected due to its moderate cytotoxic effect on both cell lines. The effect of Epibrassinolide treatment is examined on cell proliferation by counting the cell number within 96 h. A higher and earlier inhibition of cell proliferation is observed in LNCaP than DU145 cells.
安全信息
| 危险类别码 | 22-36/37/38 |
|---|---|
| 安全说明 | 22-36/37/39-45 |
| WGK Germany | 3 |
| 海关编码 | 29372900 |
| 提供商 | 语言 |
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英文
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| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/01/25 | HY-N0848 | Epibrassinolide | 1 mg | 327元 | |
| 2024/01/25 | HY-N0848 | 表油菜素内酯 Epibrassinolide | 78821-43-9 | 5mg | 720元 |