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| | N-[(S)-(+)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanine Basic information |
| | N-[(S)-(+)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanine Chemical Properties |
| Melting point | 150-152 °C(lit.) | | Boiling point | 422.1°C (rough estimate) | | alpha | +28° (20℃/D)(c=1, CH3OH) | | density | 1.1083 (rough estimate) | | vapor pressure | 1.95hPa at 25℃ | | refractive index | 29.5 ° (C=1, MeOH) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | 6g/l | | pka | 2.14±0.10(Predicted) | | form | Crystalline Powder | | color | White | | optical activity | [α]20/D +28°, c = 1 in methanol | | Water Solubility | 100mg/L at 25℃ | | BRN | 3619501 | | LogP | 0.12 at 25℃ | | CAS DataBase Reference | 82717-96-2(CAS DataBase Reference) |
| | N-[(S)-(+)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanine Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | Moexipril intermediate; the main metabolite of Imidapril. | | Uses | An intermediate in the synthesis of Ramipril | | Flammability and Explosibility | Non flammable |
| | N-[(S)-(+)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanine Preparation Products And Raw materials |
| Raw materials | Benzenebutanoic acid, α-[[(1S)-1-methyl-2-oxo-2-(phenylmethoxy)ethyl]amino]-, ethyl ester, (αS)--->Benzenebutanoic acid, α-[[(1S)-2-(1,1-dimethylethoxy)-1-methyl-2-oxoethyl]amino]-, ethyl ester, (αS)--->Benzenebutanoic acid, a-bromo-, ethyl ester-->Benzenebutanoic acid, α-[[(1S)-1-methyl-2-oxo-2-(phenylmethoxy)ethyl]amino]-γ-oxo-, ethyl ester, (αS)--->DL-Homophenylalanine-->L-Alanine benzyl ester 4-toluenesulfonate-->L-Homophenylalanine ethyl ester hydrochloride-->2-bromo-4-phenylbutyric acid-->L-Ala-OtBU.HCl-->L-Homophe-OH-->Enalapril diketopiperazine-->L-Homophenylalanine ethyl ester-->Ethyl trans-3-Benzoylacrylate-->L-ALANINE BENZYL ESTER-->Enalapril-->Enalaprilat-->2-acetamido-4-phenyl-butanoic acid-->L-Proline |
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