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L(+)-Homoarginine hydrochloride

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CAS:1483-01-8
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CAS:1483-01-8
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CAS:1483-01-8
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CAS:1483-01-8
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Products Intro: Product Name:L(+)-Homoarginine hydrochloride
CAS:1483-01-8
Purity:99% Package:5KG;1KG Remarks:C7H17ClN4O2

L(+)-Homoarginine hydrochloride manufacturers

  • L-Homoarg.hcl
  • L-Homoarg.hcl pictures
  • $0.00/ kg
  • 2024-04-24
  • CAS:1483-01-8
  • Min. Order: 1kg
  • Purity: 98%
  • Supply Ability: 1T+
L(+)-Homoarginine hydrochloride Basic information
Product Name:L(+)-Homoarginine hydrochloride
Synonyms:L-HOMOARGININE HYDROCHLORIDE, UNNATU;L-(S)-2-AMINO-6-GUANIDINOHEXANOIC ACID HYDROCHLORIDE;L(+)-HOMOARGININE HCL;L-HOMOARGININE HCL;L(+)-HOMOARGININE HYDROCHLORIDE;L-HOMOARGININE HYDROCHLORIDE;L-HOMOARGININE MONOHYDROCHLORIDE;H-HAR-OH HCL
CAS:1483-01-8
MF:C7H17ClN4O2
MW:224.69
EINECS:216-045-6
Product Categories:Aliphatics;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Amino Acids & Derivatives;Nitric Oxide Reagents;Homoarginine [HomoArg];Amino Acids 13C, 2H, 15N
Mol File:1483-01-8.mol
L(+)-Homoarginine hydrochloride Structure
L(+)-Homoarginine hydrochloride Chemical Properties
Melting point 213-215 °C(lit.)
alpha 18 º (c=1, 1N HCl)
storage temp. Inert atmosphere,Room Temperature
solubility H2O: 50 mg/mL, clear to slightly hazy, faintly yellow
form Granular Powder
color White
Water Solubility Soluble in water(50 mg/mL).
BRN 4016621
Stability:Moisture Sensitive
CAS DataBase Reference1483-01-8(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 24/25-36/37/39-27-26
WGK Germany 3
HS Code 29252900
MSDS Information
ProviderLanguage
L(+)-Homoarginine hydrochloride English
SigmaAldrich English
ACROS English
L(+)-Homoarginine hydrochloride Usage And Synthesis
DescriptionL-Homoarginine is an uncompetitive and organ-specific inhibitor of alkaline phosphatases. This non-essential amino acid inhibits human bone and liver alkaline phosphatases but has no effect on placental or intestinal isoenzymes. In vitro, L-homoarginine inhibits [3H]thymidine uptake by mouse myeloma MOPC 104E cells and inhibits proliferation of C3H/He mouse osteosarcoma cells. Pre-treatment with L-homoarginine delays in vivo tumor growth in a murine C3H/He osteosarcoma model. It also inhibits high-protein diet-induced pancreatic growth and enzyme secretion in bile-pancreatic juice-diverted rats, a model for the induction of pancreatic enzyme secretion with hypercholecystokininemia.
Chemical PropertiesWhite Powder
UsesAn inhibitor of alkaline phosphatase isoenzymes. It is also an inhibitor of cellular transport of arginine by a sodium-independent high affinity y+ transporter. The substitution of homoarginine for arginine or lysine renders proteins resistant to proteolysis by trypsin. Arginine residues are often located at the active centers of proteins and enzymes. Replacing these arginines with homoarginine can elucidate protein function and structural requirements.
UsesAn inhibitor of alkaline phosphatase isoenzymes. An analog of Homoarginine (H585000).
Biochem/physiol ActionsHomoarginine is an inhibitor of tissue nonspecific alkaline phosphatase (TNALP). It is also an inhibitor of cellular transport of arginine by a sodium-independent high affinity y+ transporter.
L(+)-Homoarginine hydrochloride Preparation Products And Raw materials
Tag:L(+)-Homoarginine hydrochloride(1483-01-8) Related Product Information
ARGINASE L(+)-Arginine Homoarginine Topotecan hydrochloride 6-Aminocaproic acid L-Arginine hydrochloride Glycine Boc-N'-Nitro-L-homoarginine FMOC-HOMOARG(PMC)-OH N-ALPHA-T-BUTOXYCARBONYL-L-HOMOARGININE HYDROCHLORIDE,Boc-L-Homoarginine hydrochloride arginine aspirin D-Homoarginine hydrochloride 6-GUANIDINOHEXANOIC ACID FMOC-HOMOARG-OH Fmoc-N-Pbf-L-HomoArginine FMOC-L-HOMOARGININE, HYDROCHLORIDE SALT BOC-HOMOARG(ET)2-OH Z-HOMOARG-OH