|
|
| | Dimethyldioctadecylammonium bromide Basic information |
| | Dimethyldioctadecylammonium bromide Chemical Properties |
| Hazard Codes | Xi | | Risk Statements | 36/37/38-43 | | Safety Statements | 26-37/39 | | WGK Germany | 3 | | TSCA | Yes | | HazardClass | 9 | | HS Code | 29211990 |
| | Dimethyldioctadecylammonium bromide Usage And Synthesis |
| Description | 18:0 DDAB is a double-chained quaternary ammonium surfactant with a bromide counter ion. | | Chemical Properties | white powder | | Uses | Dimethyldioctadecylammonium bromide has been used in a study to assess the interaction of its monolayers with DNA using specular neutron reflection, surface pressure-area isotherms, and Brewster angle microscopy. It has also been used in a study to investigate new adjuvants for use in kill vaccines for bovine viral diarrhea virus (BVDV). | | General Description | 18:0 DDAB is cationic lipid and a quaternary ammonium salt. The hydrocarbon tails are saturated unlike the ionizable lipids. | | Biochem/physiol Actions | 18:0 DDAB is a surface-active molecule, used as an adjuvant to induce systemic immune response. It is non-toxic. | | Purification Methods | Crystallise the bromide from acetone, then MeOH [Lukac J Am Chem Soc 106 4387 1984]. Also purify it by chromatography on alumina by washing with *C6H6 and eluting with Me2CO, evaporating and crystallising from MeCN [Swain & Kreevoy J Am Chem Soc 77 1126 1955]. [Beilstein 4 IV 829.] |
| | Dimethyldioctadecylammonium bromide Preparation Products And Raw materials |
|