灵芝酸A
| 中文名称 | 灵芝酸A |
|---|---|
| 中文同义词 | 灵芝酸A;灵芝酸 A(96%);灵芝酸 A, 来源于灵芝;灵芝酸A(95%);灵芝酸A(标准品);GANODERENIC ACID A 灵芝酸A;灵芝酸 A?, >98%;JAK-STAT3信号通路抑制剂(GANODERIC ACID A) |
| 英文名称 | GANODERIC ACID A |
| 英文同义词 | (2R,6R)-6-((7S,10S,13R,14R,15S,17R)-7,15-Dihydroxy-4,4,10,13,14-pentaMethyl-3,11-dioxo-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-Methyl-4-oxoheptanoic acid;(2R,6R);-2-methyl-4-oxoheptanoic acid;-6-((7S,10S,13R,14R,15S,17R);-7,15-Dihydroxy-4,4,10,13,14-pentamethyl-3,11-dioxo-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl);(25R)-7β,15α-Dihydroxy-3,11,23-trioxo-5α-lanost-8-en-26-oic acid;Aids070759;Aids-070759 |
| CAS号 | 81907-62-2 |
| 分子式 | C30H44O7 |
| 分子量 | 516.67 |
| EINECS号 | |
| 植物来源 | 灵芝 |
| 相关类别 | 对照品;中药对照品;植提标准品;植物提取物;对照品、标准品、植物单体;对照品，标准品，生物试剂，植物单体;标准品;chemical reagent;pharmaceutical intermediate;分析试剂标准品;标准品-对照品;细胞生物学试剂;三萜;标准品 -中药标准品;标准品，对照品;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract |
| Mol文件 | 81907-62-2.mol |
| 结构式 |  |
灵芝酸A 性质
| 熔点 | 118～123℃ |
|---|---|
| 沸点 | 690.1±55.0 °C(Predicted) |
| 密度 | 1.22 |
| 储存条件 | Sealed in dry,Store in freezer, under -20°C |
| 溶解度 | 可溶于氯仿（轻微，超声处理），甲醇（轻微） |
| 形态 | 固体 |
| 酸度系数(pKa) | 4.78±0.23(Predicted) |
| 颜色 | 白色至浅黄色 |
|
Human Endogenous Metabolite
|
A lower doses of Ganoderic acid A enhance HLA class II-mediated antigen presentation and CD4+ T cell recognition of lymphoma.
Ganoderic acid A promots cisplatin-induced cell death by enhancing the sensitivity of HepG2 cells to cisplatin mainly via the signal transducer and activator of transcription 3 suppression.
Ganoderic acid Ainhibits proliferation, viability, ROS, DPPH, and analyzed the expression of SOD1, SOD2, and SOD3 by Real time PCR in a PC-3 cell in a dose-dependent manner.
Ganoderic acid A effectively inhibites the proliferation of human osteosarcoma HOS and MG-63 cells in a dose-dependent manner, and induced obvious cell apoptosis in both cells.
Ganoderic acid A treatment significantly prolonged survival of EL4 challenged mice and decreased tumor metastasis to the liver.
药理药效:抑制细胞组织胺的释放，增强消化系统各种器官的机能，具有降血脂、降血压、护肝、调节肝功能等作用。
安全信息
| 安全说明 | 24/25 |
|---|---|
| 海关编码 | 29189900 |
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/01/25 | HY-N1447 | 灵芝酸A Ganoderic acid A | 81907-62-2 | 1mg | 500元 |
| 2024/01/25 | HY-N1447 | 灵芝酸A Ganoderic acid A | 81907-62-2 | 5mg | 1250元 |