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gamma-Butyrolactone Suppliers list
Company Name: Hefei TNJ Chemical Industry Co.,Ltd.
Tel: 86-0551-65418684 18949823763
Products Intro: Product Name:gamma-Butyrolactone
Purity:99.9%min. Package:1KG;4USD
Company Name: Tianjin Zhongxin Chemtech Co., Ltd.
Tel: 022-89880739
Products Intro: Product Name:gamma-Butyrolactone
Purity:99.5%Min Package:200kg drum Remarks:GBL
Company Name: Capot Chemical Co.,Ltd.
Tel: +86 (0)571-855 867 18
Products Intro: Product Name:γ-Butyrolactone
Purity:98%(Min,GC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: Shenzhen Sendi Biotechnology Co.Ltd.
Tel: 0755-23311925 18102838259
Products Intro: Product Name:gamma-Butyrolactone
Purity:99% Package:16/KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Products Intro: CAS:96-48-0
Purity:99% Package:500G;1KG;5KG;25KG
gamma-Butyrolactone Basic information
Chemical properties Uses Production Category Toxicity grading Acute toxicity Hazardous characteristics of the explosive Flammability hazard Storage and transportation properties Extinguishing agent
Product Name:gamma-Butyrolactone
Synonyms:1-Oxacyclopentan-2-one;2(3H)-dihydrofuranone;2(3H)-Furanone, dihydro-;2(3H)-furanone,dihydro-;2,3,4,5-tetrahydro-2-furanone;2-Oxolanone;2-Oxotetrahydrofuran;3-Hydroxybutyric acid lactone
Product Categories:Pharmaceutical Intermediates;Heterocycles;Miscellaneous Reagents;Halogenated Heterocycles ,Thiophenes ,Thiazolines/Thiazolidines
Mol File:96-48-0.mol
gamma-Butyrolactone Structure
gamma-Butyrolactone Chemical Properties
Melting point −45 °C(lit.)
Boiling point 204-205 °C(lit.)
density 1.12 g/mL at 25 °C(lit.)
vapor density 3 (vs air)
vapor pressure 1.5 mm Hg ( 20 °C)
refractive index n20/D 1.436(lit.)
Fp 209 °F
storage temp. 2-8°C
explosive limit16%
Water Solubility MISCIBLE
Merck 13,1596
Stability:Stable. Hygroscopic. Incompatible with strong oxidizing agents, strong acids, strong bases, strong reducing agents.
CAS DataBase Reference96-48-0(CAS DataBase Reference)
NIST Chemistry Reference«gamma»-Butyrolactone(96-48-0)
EPA Substance Registry System2(3H)-Furanone, dihydro-(96-48-0)
Safety Information
Hazard Codes Xn,F
Risk Statements 22-36-67-41-20/21/22-11
Safety Statements 26-36-39-36/37-16
WGK Germany 1
RTECS LU3500000
HS Code 29322980
Hazardous Substances Data96-48-0(Hazardous Substances Data)
MSDS Information
BLO English
SigmaAldrich English
ACROS English
gamma-Butyrolactone Usage And Synthesis
Chemical propertiesColorless transparent liquid It is miscible with water and the general organic and slightly soluble in aliphatic hydrocarbons.
  • It is an important organic synthesis intermediate which can be used to synthesize indole butyric acid, butyric acid, succinic acid, α-pyrrolidone, N-methylpyrrolidone, vinyl pyrrolidone, acetyl-γ-butyrolactone, cyclopropylamine, ciprofloxacin, vitamin B1, chlorophyll and so on;
  • It is a non-toxic high boiling point solvent with high solubility and safe and convenient usage and management;
  • It is used as an extractant for butadiene, aromatic, advanced grease petroleum processing;
  • It is used as an acrylonitrile fiber spinning solvent in the chemical fiber industry. 
  • It is a thinner and curing agent commonly used in wool, nylon, acrylonitrile and other fiber dyeing auxiliaries and other chemical industries.
ProductionMaleic anhydride hydrogenation method is an advanced technology developed in 1970s. It can produce tetrahydrofuran and γ-butyrolactone in any proportion with a hydrogenation reaction, and the usual ratio is tetrachlorofuran: γ-butyrolactone = 3-4:1.
There are many production enterprises, but usually in small scale. The average level is 300t/a. The production capacity account for 30% of the total domestic production capacity.  2.1, 4-butanediol dehydrogenation reactor is a tube array reactor, filled with flake copper catalyst (with zinc oxide as the carrier). The reaction temperature is controlled at 230-240 ° C. The yield of the product is obtained by reduced pressure distillation of and the yield is above 77%.
CategoryFlammable substance
Toxicity gradingMiddle
Acute toxicityoral-rat LD50: 1540 mg/kg; oral-mouse LD50: 1720 mg/kg
Hazardous characteristics of the explosiveExplosible when react with butanol, 2,4-dichlorophenol and sodium hydroxide
Flammability hazardFlammable in case of heat, open flame; being able to react with oxidant; releasing toxic pungent smoke when in the process of pyrolysis.
Storage and transportation propertiesMake sure ventilating, low temperature and drying in the warehouse; separate from the oxidant; prevent fires.
Extinguishing agentDry powder, carbon dioxide, foam
Chemical Propertiescolourless oily liquid
Usesr-butyrolactone is one kind of important fine chemicalintermediate, simultaneously also is one kind of performance fine highboiling point solvent, ideal antioxidant, plasticizer,extracting agent, absorbent, dispersing agent, solid stain, Coagulation Reagent.
DefinitionChEBI: A butan-4-olide that is tetrahydrofuran substituted by an oxo group at position 2.
UsesIntermediate in the synthesis of polyvinylpyrrolidone, DL-methionine, piperidine, phenylbutyric acid, thiobutyric acids. Solvent for polyacrylonitrile, cellulose acetate, methyl methacrylate polymers, polystyrene. Constituent of paint removers, textile aids, drilling oils.
General DescriptionClear colorless oily liquid with a pleasant odor.
Air & Water ReactionsHygroscopic. Soluble in water.
Reactivity Profilegamma-Butyrolactone can react with oxidizing materials, inorganic acids and bases, alcohols and amines. Rapidly hydrolyzed by bases and slowly hydrolyzed by acids. gamma-Butyrolactone is volatile with steam. . The combination of the lactone, butanol, 2,4-dichlorophenol, and sodium hydroxide in the attempted synthesis of 2,4-dichlorophenoxybutyric acid caused a thermal runaway reaction that eventually exploded, [CISHC Chem. Safety Summ., 1977, 48, 3].
Fire Hazardgamma-Butyrolactone is combustible.
Tag:gamma-Butyrolactone(96-48-0) Related Product Information
D-(-)-Gulonic acid gamma-lactone Cyclobutane-1,2,3,4-tetracarboxylic dianhydride 6-Amino-4-hydroxy-2-naphthalenesulfonic acid Succinic anhydride 2,3,4-Trihydroxybenzoic acid Di-tert-butyl dicarbonate Isobutyric acid Erythromycin 2'-propionate dodecyl sulfate BETA-BUTYROLACTONE 4-Cyanophenol gamma-Butyrolactone Maleic anhydride 4-Aminobutyric acid Phthalic anhydride Acetic anhydride Glutaric anhydride TRIOXSALEN (-)-Corey lactone diol