パルミチン酸 エチル(628-97-7)

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パルミチン酸 エチル 製品概要
化学名:パルミチン酸 エチル
英語化学名:Palmitic acid ethyl ester
别名:Ethyl cetylate;ETHYL N-HEXADECANOATE;Ethyl palmitate, (Ethyl hexadecanoate;Palmitic aci;FATTY ALCOHOLS ETHOXYLATED;ETHYL PALMITATE 95+%;Ethylpalmitate,97%;Palmitic acid ethyl
CAS番号:628-97-7
分子式:C18H36O2
分子量:284.48
EINECS:211-064-6
カテゴリ情報:Fatty Acid Derivatives & Lipids;Glycerols;Inhibitors
Mol File:628-97-7.mol
パルミチン酸 エチル
パルミチン酸 エチル 物理性質
融点 24-26 °C (lit.)
沸点 192-193 °C/10 mmHg (lit.)
比重(密度) 0.857 g/mL at 25 °C (lit.)
蒸気圧0.01Pa at 25℃
FEMA 2451 | ETHYL PALMITATE
屈折率 n20/D 1.440(lit.)
闪点 >230 °F
貯蔵温度 2-8°C
溶解性Chloroform (Slightly), Ethyl Acetate (Slightly)
Colourless to Off-White
比重0.857
臭い (Odor)at 100.00 %. mild waxy fruity creamy milky balsamic greasy oily
においのタイプwaxy
水溶解度 IMMISCIBLE
JECFA Number39
BRN 1782663
Dielectric constant2.7(103℃)
LogP7.74
CAS データベース628-97-7(CAS DataBase Reference)
NISTの化学物質情報Hexadecanoic acid, ethyl ester(628-97-7)
EPAの化学物質情報Hexadecanoic acid, ethyl ester (628-97-7)
安全性情報
主な危険性 Xi
Sフレーズ 23-24/25
WGK Germany 3
Hazard Note Irritant
TSCA Yes
HSコード 29157020
MSDS Information
ProviderLanguage
Palmitic acid ethyl ester English
SigmaAldrich English
ACROS English
ALFA English
パルミチン酸 エチル Usage And Synthesis
外観白色/無色~うすい黄色粉末~塊~透明液体
定義本品は、パルミチン酸(*)とエタノール(*)とのエステルであり、次の化学式で表される。
参照表示名称:パルミチン酸, エタノール
溶解性エタノール及びアセトンに溶け、水にほとんど溶けない。
用途有機合成原料、香料材料。
化粧品の成分用途エモリエント剤、ヘアコンディショニング剤、香料
説明Palmitic acid ethyl ester, also known as ethyl palmitate, it the ethyl ester form of palmitic acid. It can be used as a hair- and skin-conditioning agent. It has been shown that the combination between palmitic acid ethyl ester and cobra venom factor can enhance the survival of heterologous erythrocyte. Recent study has also demonstrated the potential anti-inflammatory activity of palmitic acid ethyl ester in several animal models.
化学的特性clear colorless oily liquid after melting
化学的特性Ethyl palmitate has a mild, waxy sweet odor. It is nearly tasteless and has a creamy mouthfeel.
天然物の起源Reported found in mutton, rye bread, rice, bourbon, vanilla, red sage, lemon balm, bilberry, Parmesan cheese, maple syrup, Jamaican rum, whiskey, grape wine, cognac, cocoa, green tea, mango, corn oil and mastic gum leaf oil.
使用A fatty acid found in Amaranth oil; it shows inhibitory activity.
使用Ethyl palmitate acts as a lubricant on the skin?s surfaces in order to get a soft and smooth appearance. It increases cytosolic Ca2+ concentration leading to pancreatic acinar cell injury due to excessive consumption of ethanol.
定義ChEBI: A long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of palmitic acid with the hydroxy group of ethanol.
Aroma threshold valuesDetection: 2 ppm
Taste threshold valuesTaste characteristics at 30 ppm: waxy, fruity, creamy and fermented with a vanilla, balsamic nuance.
Synthesis Reference(s)Tetrahedron, 48, p. 8775, 1992 DOI: 10.1016/S0040-4020(01)89450-3
一般的な説明Ethyl palmitate is a one of the major volatile compounds found in cooked rice and Luzhou-flavor raw liquor. It occurs naturally in licorice root and chamomile.
合成Synthesized by immobilized lipase-catalyzed alcoholysis and esterification in organic solvents.
参考文献Beste, Russell D, and R. D. Hamlin. "Skin permeation enhancer compositions comprising a monoglyceride and ethyl palmitate." US, US6267984. 2001.
Castro, O, et al. "Mechanism of ethyl palmitate and cobra venom factor enhancement of heterologous erythrocyte survival. " Proceedings of the Society for Experimental Biology & Medicine Society for Experimental Biology & Medicine 147.1(1974):106.
Saeed, N. M., et al. "Anti-inflammatory activity of methyl palmitate and ethyl palmitate in different experimental rat models. " Toxicology & Applied Pharmacology 264.1(2012):84-93.
Tags:628-97-7