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ChemicalBook >>Glibenclamide>>5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxybenzamide(10238-21-8)

5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxybenzamide(10238-21-8)

5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxybenzamide(10238-21-8)
Product IdentificationBack to Contents
【Product Name】

5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxybenzamide
【Synonyms】

5-Chloro-N-[4-(cyclohexylureidosulfonyl)phenethyl]-2-methoxybenzamide
Glyburide
N-p-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzenesulfonyl-N'-cyclohexylurea
【CAS】

10238-21-8
【Formula】

C23H28ClN3O5S
【Molecular Weight】

494.01
【EINECS】

233-570-6
【RTECS】

YS4725200
【RTECS Class】

Drug; Reproductive Effector; Human Data
【Merck】

13,4491
【Beilstein/Gmelin】

2230085
【Beilstein Reference】

6-14
Physical and Chemical PropertiesBack to Contents
【Appearance】

White solid
【Solubility in water】

1.1 mg/L (37 C)
【Melting Point】

168 - 172
【Density】

1.38 g/cm3
【pKa/pKb】

5.3(at 25℃) (pKa)
【Usage】

Hypoglycemic drug.
First Aid MeasuresBack to Contents
【Ingestion】

If swallowed, wash out mouth with water provided person is conscious. Call a physician.
【Inhalation】

If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
【Skin】

In case of contact, immediately wash skin with soap and copious amounts of water.
【Eyes】

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
Handling and StorageBack to Contents
【Storage】

Keep tightly closed. Store at 2-8 C
Hazards IdentificationBack to Contents
【Inhalation】

May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
【Skin】

May cause skin irritation. May be harmful if absorbed through the skin.
【Eyes】

May cause eye irritation.
【Ingestion】

May be harmful if swallowed.
【Hazards】

Emits toxic fumes under fire conditions.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Protective gloves. Chemical safety goggles.
【Respirators】

Wear dust mask.
【Exposure Effects】

Avoid contact and inhalation. Target organ(s): Pancreas. G.I. System.
Fire Fighting MeasuresBack to Contents
【Fire Fighting】

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability and ReactivityBack to Contents
【Stability】

Stable at normal temperatures and pressures.
【Incompatibilities】

Strong oxidizing agents.
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