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Acetylsalicylic acid(50-78-2)

Acetylsalicylic acid(50-78-2)
Product IdentificationBack to Contents
【Product Name】

Acetylsalicylic acid
【Synonyms】

2-(Acetyloxy)benzoic acid
Aspirin
o-Acetylsalicylic acid
【CAS】

50-78-2
【Formula】

C9H8O4
【Molecular Weight】

180.16
【EINECS】

200-064-1
【RTECS】

VO0700000
【RTECS Class】

Drug; Mutagen; Reproductive Effector; Human Data
【Merck】

13,856
【Beilstein/Gmelin】

779271
【Beilstein Reference】

4-10-00-00138
Physical and Chemical PropertiesBack to Contents
【Appearance】

Odorless white crystals or crystalline powder with a slightly bitter taste.
【Solubility in water】

3.3 g/L
【Boiling Point】

140
【Vapor Pressure】

.00003
【Density】

1.39 g/cm3
【pKa/pKb】

3.49 (pKa)
【Partition Coefficient】

1.19
【Heat Of Vaporization】

106.40 kJ/mol
【Heat Of Combustion】

-3927 kJ/mol
【Usage】

Medication.
【Refractive Index】

1.5623 (20 C)
First Aid MeasuresBack to Contents
【Ingestion】

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid.
【Inhalation】

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
【Eyes】

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Handling and StorageBack to Contents
【Storage】

Store in a cool, dry place. Store in a tightly closed container.
【Handling】

Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with skin and eyes. Avoid ingestion and inhalation.
Hazards IdentificationBack to Contents
【Inhalation】

May cause respiratory tract irritation. Can produce anaphylactic shock with even small doses.
【Skin】

May cause skin irritation. Low hazard for usual industrial handling. Chronic ingestion may result in salicylism which is characterized by nausea, vomiting, gastrointestinal ulcers, and hemorrhagic strokes.
【Eyes】

May cause eye irritation and possible burns.
【Ingestion】

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Inhibits platelet aggregation affecting bleeding
【Hazards】

Contact with metals may evolve flammable hydrogen gas.
【EC Risk Phrase】

R 22 36/37
【EC Safety Phrase】

S 26 36/37/39
【UN (DOT)】

2811
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
【Exposure Effects】

Chronic ingestion may result in salicylism which is characterized by nausea, vomiting, gastrointestinal ulcers, and hemorrhagic strokes.
【Exposure limit(s)】

OEL-UNITED KINGDOM:TWA 5 mg/m3
【Poison Class】

3
Fire Fighting MeasuresBack to Contents
【Flash Point】

250
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: For small fires, use water spray, dry chemical, carbon dioxide or chemical foam.
【Fire Potential】

This chemical is combustible.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Vacuum or sweep up material and place into a suitable disposal container. Avoid generating dusty conditions.
Stability and ReactivityBack to Contents
【Stability】

Stable under normal shipping and handling conditions.
【Incompatibilities】

Strong alkali, hydrolyzes in moist air, decomposes in hot water.
【Decomposition】

Carbon monoxide, carbon dioxide.
【Combustion Products】

Fire may produce irritating, corrosive and/or toxic gases.
Transport InformationBack to Contents
【UN Number】

2811
【Hazard Class】

6.1
【Packing Group】

I; II; III
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