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Propantheline bromide(50-34-0)

Propantheline bromide(50-34-0)
Product IdentificationBack to Contents
【Product Name】

Propantheline bromide
【Synonyms】

(2-Hydroxyethyl)diisopropylmethylammonium bromide xanthene-9-carboxylate
2-Propanaminium, N-methyl-N-(1-methylethyl)-N-[2-[(9H-xanthen-9-ylcarbonyl)oxy]ethyl]-, bromide
Aucuboside
b-D-Glucopyranoside, 1,4a,5,7a-tetrahydro-5-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-1-yl, [1S-(1a,4a,5a,7a)]
b-Diisopropylaminoethyl xanthene-9-carboxylate methobromide
Ercotina
Neopepulsan
Prodixamon
Rhimantin
【CAS】

479-98-1
【CAS】

50-34-0
【Formula】

C15H22O9
【Formula】

C23H30BrNO3
【Molecular Weight】

448.4
【Molecular Weight】

346.33
【EINECS】

200-030-6
【EINECS】

207-540-8
【RTECS】

BP8249200
【RTECS Class】

Drug; Mutagen
【Merck】

12,7989
【Merck】

12,910
【Beilstein/Gmelin】

3643037
【Beilstein/Gmelin】

50340
【Beilstein Reference】

5-18-06-00590
Physical and Chemical PropertiesBack to Contents
【Appearance】

White crystals or white powder.
【Solubility in water】

66 g/L (25 C)
【Melting Point】

157 - 158
【Melting Point】

181
【Boiling Point】

669
【Vapor Pressure】

9.3E-21 (25 C)
【Density】

1.61 g/cm3 (20 C)
【pKa/pKb】

12.80 (pKa)
【Partition Coefficient】

-3.17
【Heat Of Vaporization】

112.5 kJ/mol
【Usage】

An antimuscarinic agent used for the treatment of excessive sweating.
【Usage】

Anti-inflammatory.
First Aid MeasuresBack to Contents
【Ingestion】

DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician.
【Ingestion】

If swallowed, wash out mouth with water provided person is conscious. Call a physician.
【Inhalation】

IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
【Inhalation】

Material may be irritating to mucous membranes and upper respiratory tract. May be harmful if inhaled.
【Inhalation】

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
【Skin】

May cause skin irritation. May be harmful if absorbed through the skin.
【Skin】

IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.
【Skin】

In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.
【Eyes】

May cause irritation.
【Eyes】

First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.
【Eyes】

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
Handling and StorageBack to Contents
【Storage】

Keep containers tightly closed.
【Storage】

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
【Handling】

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Hazards IdentificationBack to Contents
【Ingestion】

May be harmful if swallowed.
【Ingestion】

See inhalation.
【Inhalation】

Symptoms of exposure to this compound include dilated pupils and blurred vision; increased intraocular tension and heart rate; hot, dry, red skin; dry mouth; disorientation; hallucinations; aggressive behavior; rapid pulse and respiration; convulsions; and coma.
【Skin】

See inhalation.
【Eyes】

See inhalation
【Hazards】

Emits toxic fumes under fire conditions.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
【Personal Protection】

Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing.
【Respirators】

Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Respiratory protection is not required. Where protection from nuisance levels of dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks.
【Respirators】

Wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter.
Fire Fighting MeasuresBack to Contents
【Flash Point】

358
【Fire Fighting】

Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
【Fire Fighting】

Fires involving this compound should be controlled with a dry chemical, carbon dioxide or Halon extinguisher.
【Fire Potential】

This material is probably combustible.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a strong soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
【Small spills/leaks】

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability and ReactivityBack to Contents
【Stability】

No data.
【Stability】

Stable at normal temperatures and pressures.
【Incompatibilities】

Strong oxidizing agents.
【Decomposition】

Oxides of carbon.
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