| Product Identification | Back to Contents | 【Product Name】
1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl 2-methylbutanoate | 【Synonyms】
[(1S,3R,7R,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxo-oxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate
1,2,6,7,8,8a-Hexahydro-beta,delta-dihydroxy-2,6-dimethyl-8-(2-methyl-1-oxobutyoxy)-1-naphthaleneheptanoic acid delta-lactone
2beta, 6alpha-Dimethyl-8alpha-(2-methyl-1-oxobutoxy)-mevinic acid lactone
Mevinacor
Paschol
Rovacor | 【CAS】
75330-75-5 | 【Formula】
C24H36O5 | 【Molecular Weight】
404.55 | 【RTECS】
EK7907000 | 【RTECS Class】
Drug; Reproductive Effector; Human Data | 【Merck】
12,5616 | 【Beilstein/Gmelin】
3631989 |
| First Aid Measures | Back to Contents | 【Ingestion】
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended. | 【Inhalation】
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention. | 【Skin】
Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse. | 【Eyes】
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention. |
| Handling and Storage | Back to Contents | 【Storage】
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage. | 【Handling】
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood. |
| Hazards Identification | Back to Contents | 【Skin】
Dermatitis, photosensitivity, and dermatomyositis may occur following therapy with hmg-coa reductase inhibitors. | 【Ingestion】
Diarrhea and flatulence were commonly reported adverse effects during clinical trials. Pancreatitis was associated with gemfibrozil-lovastatin combined therapy. |
| Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots. | 【Respirators】
Use NIOSH/MSHA approved respirator appropriate for exposure of concern. | 【Exposure Effects】
peripheral neuropathies have been reported following therapy with the hmg-coa enzyme inhibitors. Therapeutic administration of hmg-coa enzyme inhibitors may cause insomnia, behavioral changes, and extrapyramidal symptoms. Congenital abnormalities were reported in an infant whose mother ingested dextroamphetamine and lovastatin during the first trimester. <br>Skeletal abnormalities of the ribs and vertebra have been reported in female rats administered lovastatin 800 mg/kg/day during gestation. <br>Animal studies indicate HMG-CoA enzyme inhibitors are excreted into breast milk. |
| Fire Fighting Measures | Back to Contents | 【Fire Fighting】
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire. |
| Accidental Release Measures | Back to Contents | 【Small spills/leaks】
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces. |
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| Company Name: |
J & K SCIENTIFIC LTD. |
| Tel: |
010-82848833 400-666-7788 |
| Fax: |
86-10-82849933 |
| WebSite: |
http://www.jkchemical.com |
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