ChemicalBook >>17a-Ethynyl-1,3,5(10)-estratriene-3,17b-diol 3-methyl ether>>17a-Ethynyl-1,3,5(10)-estratriene-3,17b-diol 3-methyl ether(72-33-3)

17a-Ethynyl-1,3,5(10)-estratriene-3,17b-diol 3-methyl ether(72-33-3)

17a-Ethynyl-1,3,5(10)-estratriene-3,17b-diol 3-methyl ether(72-33-3)
Product IdentificationBack to Contents
【Product Name】

17a-Ethynyl-1,3,5(10)-estratriene-3,17b-diol 3-methyl ether
【Synonyms】

19-Norpregna-1,3,5(10)-trien-20-yn-17-ol, 3-methoxy-, (17.alpha.)-
3-Methoxyethynylestradiol
8R,9S,13S,14S,17R)-17-ethynyl-3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-ol
Ethynylestradiol 3-monomethyl ether
Menophase
【CAS】

72-33-3
【Formula】

C21H26O2
【Molecular Weight】

310.44
【EINECS】

200-777-8
【RTECS】

RC8960000
【RTECS Class】

Agricultural Chemical and Pesticide; Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data; Hormone
【Merck】

12,5976
【Beilstein/Gmelin】

2625905
【Beilstein Reference】

4-06-00-06877
Physical and Chemical PropertiesBack to Contents
【Appearance】

White powder
【Solubility in water】

Practically insoluble
【Melting Point】

150 - 151.5
【Density】

1.22 g/cm3
【Usage】

Hormonal drug.
First Aid MeasuresBack to Contents
【Ingestion】

Induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
【Inhalation】

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.
【Skin】

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
【Eyes】

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Handling and StorageBack to Contents
【Storage】

Do not store in direct sunlight. Store in a tightly closed container. Hormones and antibiotics room. Store in a cool, dry area away from incompatible substances.
【Handling】

Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Use only in a chemical fume hood.
Hazards IdentificationBack to Contents
【Inhalation】

May cause respiratory tract irritation.
【Skin】

May cause skin irritation.
【Eyes】

May cause mechanical irritation.
【Ingestion】

May cause nausea and vomiting.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
【Respirators】

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
【Exposure Effects】

May cause cancer according to animal studies. Reproductive effects have been reported in humans. Cancer suspect agent.
【Poison Class】

1*
Fire Fighting MeasuresBack to Contents
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Vacuum or sweep up material and place into a suitable disposal container. Avoid generating dusty conditions. Provide ventilation.
Stability and ReactivityBack to Contents
【Stability】

Stable under normal temperatures and pressures.
【Incompatibilities】

Strong oxidizing agents, acid anhydrides.
【Decomposition】

Carbon monoxide, carbon dioxide.
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