ChemicalBook >>7-Aminocephalosporanic acid>>7-ACA(957-68-6)

7-ACA(957-68-6)

7-ACA(957-68-6)
Product IdentificationBack to Contents
【Product Name】

7-ACA
【Synonyms】

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-amino-8-oxo-, (6R,7R)-
7-ACA
7-Amino-3-acetoxymethyl-3-cephem-4-carboxylic acid
7-Amino-3-acetoxymethyl-D3-cephem-4-carboxylic acid
7b-Amino-3-acetoxymethylcephemcarboxylic acid
【CAS】

957-68-6
【Formula】

C10H12N2O5S
【Molecular Weight】

272.27
【EINECS】

213-485-0
【Merck】

13,433
【Beilstein/Gmelin】

622638
Physical and Chemical PropertiesBack to Contents
【Appearance】

Beige crystalline powder.
【Solubility in water】

Very soluble
【Melting Point】

300
【pKa/pKb】

2.59 (pKa)
First Aid MeasuresBack to Contents
【Ingestion】

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
【Inhalation】

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.
【Skin】

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
【Eyes】

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Handling and StorageBack to Contents
【Storage】

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
【Handling】

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation.
Hazards IdentificationBack to Contents
【Inhalation】

Causes respiratory tract irritation. Can produce delayed pulmonary edema. In rare instances, exposure may cause sensitization, resulting in inflammation of the mucous membranes and in eczematous eruptions.
【Skin】

Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
【Eyes】

Causes eye irritation. May cause chemical conjunctivitis.
【Ingestion】

May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
【EC Risk Phrase】

R 42/43
【EC Safety Phrase】

S 22 36/37 45
【UN (DOT)】

3335
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
【Exposure Effects】

Effects may be delayed. Repeated or prolonged exposure may cause allergic reactions in sensitive individuals.
Fire Fighting MeasuresBack to Contents
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Stability and ReactivityBack to Contents
【Stability】

Stable at room temperature in closed containers under normal storage and handling conditions.
【Incompatibilities】

Strong oxidizing agents.
【Decomposition】

Nitrogen oxides, carbon monoxide, oxides of sulfur, irritating and toxic fumes and gases, carbon dioxide, nitrogen.
Transport InformationBack to Contents
【UN Number】

3335
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