ChemicalBook >>Bestatin>>Ubenimex(58970-76-6)

Ubenimex(58970-76-6)

Ubenimex(58970-76-6)
Product IdentificationBack to Contents
【Product Name】

Ubenimex
【Synonyms】

3-(R)-Amino-2-(S)-hydroxy-4-phenylbutanoyl-(S)-leucine
Bestatin
N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine
NK-421
【CAS】

58970-76-6
【Formula】

C16H24N2O4
【Molecular Weight】

308.38
【EINECS】

261-529-2
【RTECS】

OH2915000
【RTECS Class】

Drug; Reproductive Effector; Natural Product
【Merck】

12,9973
【Beilstein/Gmelin】

4704312
【Beilstein Reference】

6-14
Physical and Chemical PropertiesBack to Contents
【Appearance】

white powder
【Solubility in water】

Soluble
【Melting Point】

231 - 234
【Vapor Pressure】

2E-15 (25 C)
【pKa/pKb】

3.60 (pKa)
【Heat Of Vaporization】

94.5 kJ/mol
【Usage】

An aminopeptidase inhibitor used in combination with chemotherapeutics for the maintenance and enhancement of complete remission of acute non-lymphocytic leukemia in adults.
First Aid MeasuresBack to Contents
【Ingestion】

If swallowed, wash out mouth with water provided person is conscious. Call a physician.
【Inhalation】

If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
【Skin】

In case of contact, immediately wash skin with soap and copious amounts of water.
【Eyes】

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
Handling and StorageBack to Contents
【Storage】

Keep tightly closed.
Hazards IdentificationBack to Contents
【Inhalation】

May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
【Skin】

May cause skin irritation. May be harmful if absorbed through the skin.
【Eyes】

May cause eye irritation.
【Ingestion】

May be harmful if swallowed.
【Hazards】

Emits toxic fumes under fire conditions.
【EC Safety Phrase】

22 24/25
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Protective gloves. Chemical safety goggles.
【Respirators】

Wear dust mask.
【Exposure Effects】

The chemical, physical, and toxicological properties of this product have not been thoroughly investigated. Exercise due care.
Fire Fighting MeasuresBack to Contents
【Flash Point】

320
【Fire Fighting】

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability and ReactivityBack to Contents
【Stability】

Stable at normal temperatures and pressures.
【Incompatibilities】

Strong oxidizing agents.
【Decomposition】

Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen chloride gas.
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