Product Name:Margatoxin
CAS No.:145808-47-5
Synonyms:Margatoxin (9CI);斑蝎毒素
Catalog No.:211P16
Brand:HongTide(上海鸿肽生物)
Description:Margatoxin 是一种有效的 KV1.3 通道阻滞剂多肽,序列中含有39个氨基酸,并且包含3对二硫键,IC50为36 pM,但对钙激活通道没有影响。Margatoxin可以减少VEGF诱导的跨膜钙流入和人内皮细胞中一氧化氮的产生。
Margatoxin is an effective KV1.3 channel blocker peptide with a sequence of 39 amino acids and 3 pairs of disulfide bonds. Its IC50 is 36 pM, but it has no effect on calcium activated channels. Margatoxin can reduce VEGF induced transmembrane calcium influx and nitric oxide production in human endothelial cells.
Purity (HPLC) ≥75.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) |
TIINVKCTSPKQCLPPCKAQFGQSAGAKCMNGKCKCYPH(Disulfide bridge:Cys7-Cys29;Cys13-Cys34;Cys17-Cys39) |
Sequence(3-letter code) |
H-Thr-Ile-Ile-Asn-Val-Lys-Cys-Thr-Ser-Pro-Lys-Gln-Cys-Leu-Pro-Pro-Cys-Lys-Ala-Gln-Phe-Gly-Gln-Ser-Ala-Gly-Ala-Lys-Cys-Met-Asn-Gly-Lys-Cys-Lys-Cys-Tyr-Pro-His-OH(Disulfide bridge:Cys7-Cys29;Cys13-Cys34;Cys17-Cys39) |
Peptide Structure |
|
Molecular Formula | C178H286N52O50S7 |
Molecular Weight | 4178.94 |
订购联系方式:
上海鸿肽生物科技有限公司
手机: +86-18018095145 (同微信号)
QQ: 3259098395
邮箱:sales1@hongtide.com
关键字: Margatoxin;145808-47-5;Margatoxin (9CI);斑蝎毒素;多肽;
上海鸿肽生物科技有限公司(简称:鸿肽生物)是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖:定制多肽、目录多肽、氨基酸衍生物、小分子化合物;公司自成立以来,秉持“用质量作船, 以服务为帆,为科研服务”的企业理念,为国内外众多科研工作者提供了优质的服务及产品。