Product Name：[Pyr3]-Amyloid β-Protein (3-42)
CAS No.：183449-57-2
Synonyms：淀粉样蛋白[Pyr3]-Amyloid β-Protein (3-42)
Catalog No.：107P96
Brand：HongTide（上海鸿肽生物）
Description：[Pyr3]-Amyloid β-Protein (3-42)是β淀粉样肽的改造序列，选取序列中第3-42个氨基酸，序列中第1个氨基酸由Glu换成Pyr。发现 (Pyr³)-淀粉样蛋白 β-蛋白 (3-42) 是沉积在阿尔茨海默病和唐氏综合症患者大脑中的主要淀粉样蛋白 β-肽结构。 因此，建议 (Pyr³)-Aβ (3-42) 在大脑中积累并触发不溶性淀粉样蛋白 β-肽沉积物的形成。 [Pyr3]-Amyloid β-Protein (3-42)可用于研究截短的 Aβ 序列的朊病毒样行为和 tau 依赖性细胞毒性。
[Pyr3] - Amyloid β- Protein (3-42) is β The modified sequence of amyloid peptide was selected, with the 3rd to 42nd amino acids in the sequence, and the first amino acid in the sequence was replaced by Pyr instead of Glu. Discovery (Pyr ³)- Amyloid protein β- Protein (3-42) is the main amyloid protein deposited in the brain of patients with Alzheimer's disease and Down syndrome β- Peptide structure. Therefore, it is recommended that (Pyr ³)- A β (3-42) Accumulation and triggering of insoluble amyloid protein in the brain β- The formation of peptide deposits. [Pyr3] - Amyloid β- Protein (3-42) can be used to study truncated A β Prion like behavior and tau dependent cytotoxicity of sequences.
Purity (HPLC) ≥75.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | Pyr-FRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA |
Sequence(3-letter code) | Pyr-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH |
Peptide Structure | ![[Pyr3]-Amyloid β-Protein (3-42) 183449-57-2.png](/SupplyImg/2023-06-09/6382190476393841092167364.jpg "[Pyr3]-Amyloid β-Protein (3-42) 183449-57-2.png")
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Molecular Formula | C196H299N53O55S |
Molecular Weight | 4309.97 |
订购联系方式：
上海鸿肽生物科技有限公司
手机： +86-18018095145 （同微信号）
QQ: 3259098395
邮箱：sales1@hongtide.com
关键字： [Pyr3]-Amyloid β-Pro;183449-57-2;淀粉样蛋白;多肽;多肽合成;
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