Product Name：LSKL
CAS No.：283609-79-0
Synonyms：Inhibitor of Thrombospondin TSP-1；抑制剂多肽LSKL
Catalog No.：209P03
Brand：HongTide（上海鸿肽生物）
Description：LSKL是由4个氨基酸组成的抑制剂多肽，是一种与潜伏期相关肽衍生的多肽，可抑制TGF-β的血小板反应蛋白（TSP-1）活化，并防止肝损伤、纤维化；同时，LSKL可以轻松穿越血脑屏障，减轻脑积水；LSKL可通过拮抗TSP-1来成功减弱TGF-β-Smad信号的激活，但不能降低TSP-1的蛋白表达；LSKL还能促进肝切除术后肝细胞增殖。
LSKL is an inhibitor peptide composed of four amino acids, which is derived from latency related peptides and can inhibit TGF- β Activation of platelet reactive protein (TSP-1) and prevention of liver injury and fibrosis; At the same time, LSKL can easily cross the Blood–brain barrier to reduce Hydrocephalus; LSKL can successfully weaken TGF by antagonizing TSP-1- β- The activation of Smad signal cannot reduce the protein expression of TSP-1; LSKL can also promote hepatocyte proliferation after Hepatectomy.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | LSKL-NH2 |
Sequence(3-letter code) | H-Leu-Ser-Lys-Leu-NH2 |
Peptide Structure | 
|
Molecular Formula | C21H42N6O5 |
Molecular Weight | 458.59 |
订购联系方式：
上海鸿肽生物科技有限公司
手机： +86-18018095145 （同微信号）
QQ: 3259098395
邮箱：sales1@hongtide.com
关键字： LSKL ;283609-79-0;抑制剂多肽LSKL;多肽;多肽合成;
上海鸿肽生物科技有限公司（简称：鸿肽生物）是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖：定制多肽、目录多肽、氨基酸衍生物、小分子化合物；公司自成立以来，秉持“用质量作船， 以服务为帆，为科研服务”的企业理念，为国内外众多科研工作者提供了优质的服务及产品。