Rabbit Anti-Phospho-Met (Tyr1234 + Tyr1235) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Phospho-Met (Tyr1234 + Tyr1235)
IR:Immunogen Range:KE(p-Y)(p-Y)SV
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:4233
Swiss Prot:P08581
Source:KLH conjugated synthesised phosphopeptide derived from human MET around the phosphorylation site of Tyr1234/1235:KE(p-Y)(p-Y)SV
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. [provided by RefSeq, May 2016]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
Rabbit
Sheep
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: Phospho-Met (Tyr1234;Met(Phospho-Tyr1234);Met (c-Met) (phospho;c-Met (phospho Y1234;HGF/SF receptor;Proto-oncogene c-Met;MET proto-oncogene;MET_HUMAN;
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