中文名:匹伐他汀钙
英文名:Pitavastatin Calcium
中文别名:匹伐他汀钙
英文别名:Pitavastatin calcium|147526-32-7|Pitavastatin hemicalcium|Livalo|Itavastatin calcium|NK-104|Flovas|Pitavastatin calcium salt|UNII-IYD54XEG3W|IYD54XEG3W|NK 104 (acid)|Nisvastatin|CCRIS 8652|Calcium (3R,5S,E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl
纯度:≥99%
货号:P129617
包装:10mg、250mg、50mg
Cas号:147526-32-7
存储温度:-20°C储存
产品介绍:
Pitavastatin Calcium is a competitive inhibitor of the enzyme HMGCR (HMG-CoA reductase) results in a reduction in LDL cholesterol synthesis. Alternate studies show that pitavastatin can suppress oxygen production in endothelial cells by inhibiting NADPH oxidase. In addition, pitavastatin reduces the expression of eNOS mRNA while increasing the NO dependent response stimulated by acetylcholine and the calcium ionophore, A23187. Furthermore, pitavastatin inhibits the up-regulation of conductance calcium-activated potassium channels by lowering cholesterol levels in cells.A competitive inhibitor of HMG-CoA reductase
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