product name: Picroside II
cas no.:39012-20-9
chemical name;(1aS-(1aalpha,1bbeta,2beta,5abeta,6beta,6aalpha))-1a,1b,2,5a,6,6a-Hexahydro-6-((4-hydroxy-3-methoxybenzoyl)oxy)-1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl-beta-D-glucopyranoside
molecular formula:C23H28O13
molecular weight: 512.47
solubility: soluble in Pyridine, Methanol
appearance: powder
purity by hplc: >98%
biological activity:Picroside II has potent anti-apoptotic activity against renal I/R injury, by suppressing the TLR4/NF-κB signaling pathway; Picroside II can protect the ischemic kidney against renal fibrosis and its mechanism may be through the inhibition of the long term inflammation.
关键字: 胡黄连苷II;Picroside II;Amphicoside II;6-Vanilloylcatalpol
上海水正生物医药科技有限公司(Arethusa-水正生物)是一家专业从事高纯度天然药物单体的研发及销售的科技型企业。主营业务包括中药对照品、植物标准品、天然药物活性单体、药物杂质分离纯化、工艺开发研究及技术外包服务。
水正生物致力于构建全球最有影响力的“大规模、高质量天然产物库”,为全球创新药物研发机构提供丰富的物质基础,为全产业发展搭建基础性支撑平台。该库现已拥有3,000余种结构类型多样的天然化合物,几乎涵盖绝大部分已知的天然产物结构类型,其中超过60%的产品无法从商业渠道获得或现货供应商极少,它们源于650多种药用植物或真菌(包括部分中药),并且品种仍在持续丰富。