Lorcaserin Hydrochloride Hemihydrate
Synonyms:Belviq;(1R)-8-Chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine hydrochloride hemihydrate;(R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine dihydrochloride hydrate;R-Lorcaserin hydrochloride hemehydrate;Lorcaserin HCl Hemihydrate
CAS:856681-05-5
MF:2(C11H14ClN).2(HCl).H2O
Standard:Enterprise Standard
Chemical Properties: White or Nearly White Crystalline Powder
Assay:99%+
Usage
1) Appetite depressant.Agent that is used to decrease appetite.
2) Serotonergic agonist: An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.
Packing:1kg/ Foil bag
Uses for Lorcaserin Hydrochloride:
Obesity
Adjunct to caloric restriction and increased physical activity in the chronic management of obesity.
Used in patients who are obese (pretreatment body mass index [BMI] ≥30 kg/m2); also used in over
weight patients with pretreatment BMI ≥27 kg/m2 in the presence of a weight-related risk factor or
disease (e.g., hypertension, type 2 diabetes mellitus, dyslipidemia).
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Indicated only for monotherapy; safety and efficacy in combination with other weight loss products (prescription drugs [e.g., phentermine], OTC drugs, herbal preparations) not established.
Long-term effects on cardiovascular morbidity and mortality associated with obesity not established; safety and efficacy beyond 2 years of use not established.
TEST ITEMS SPECIFICATION RESULTS
Description White powder Conforms
Moisture ≤1% 0.34%
Density 1.073 1.075
Assay ≥98.5% 99.31%
Heavy Metal ≤10ppm Conforms
LK Acetone 0.5% Conforms
Ethyl acetate 0.5%
Dichloromethane 0.06%
Conclusion The specification conform with the above specifications