HEXACHLOROBENZENE

Carcinogenicity, Category 1B

Specific target organ toxicity – repeated exposure, Category 1

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

H225 Highly Flammable liquid and vapour

H319 Causes serious eye irritation

H336 May cause drowsiness or dizziness

H350 May cause cancer

H372 Causes damage to organs through prolonged or repeated exposure

H410 Very toxic to aquatic life with long lasting effects

H411 Toxic to aquatic life with long lasting effects

P201 Obtain special instructions before use.

P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P273 Avoid release to the environment.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313 IF exposed or concerned: Get medical advice/attention.

P501 Dispose of contents/container to..…

P203 Obtain, read and follow all safety instructions before use.

P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

P260 Do not breathe dust/fume/gas/mist/vapours/spray.

P264 Wash ... thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P273 Avoid release to the environment.

P318 IF exposed or concerned, get medical advice.

P319 Get medical help if you feel unwell.

P391 Collect spillage.

P405 Store locked up.

P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

no data available

Fresh air, rest. Refer for medical attention.

Rinse and then wash skin with water and soap. Refer for medical attention .

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Refer for medical attention .

Harmful by dust inhalation or if swallowed. Irritating to eyes, skin and mucous membranes. Prolonged periods of ingestion may cause cutaneous porphyria. (USCG, 1999)

Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Lindane and related compounds

Use water spray, foam, powder, carbon dioxide.

Special Hazards of Combustion Products: They contain highly toxic chloride fumes. Behavior in Fire: Produces highly toxic chloride fumes. (USCG, 1999)

Use water spray, foam, powder, carbon dioxide.

Personal protection: chemical protection suit and particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into sealable containers. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment.

Personal protection: chemical protection suit and particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into sealable containers. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment.

Absorb the spills with paper towels or like materials. Place in hood to evaporate followed by burning the towel. Dissolve in a combustible solvent. Scatter the spray of the solution into the furnace with after burners and alkali scrubber.

NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Separated from food and feedstuffs. Well closed.Separated from food and feedstuffs. Well closed.

TLV: 0.002 mg/m3, as TWA; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans).MAK: skin absorption (H); carcinogen category: 4; pregnancy risk group: D

no data available

Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.

Wear face shield or eye protection in combination with breathing protection.

Protective gloves. Protective clothing.

Use local exhaust or breathing protection.

no data available

Decomposes on heating. This produces toxic fumes.

Very stable, even to acids and bases.

Not flammable or combustible.HEXACHLOROBENZENE reacts violently with dimethylformamide. (NTP, 1992).

no data available

Dimethyl formamide and hexachlorobenzene react violently above 65 deg c.

Dangerous; When heated to decomposition, emits toxic fumes of /hydrogen chloride/.

no data available

no data available

no data available

no data available

NTP: Reasonably anticipated to be a human carcinogen

One human study reported abnormal physical development in young children who ingested contaminated bread during a 4-year poisoning incident. Hexachlorobenzene has been found to decrease the survival rates of newborn animals and to cross the placenta and accumulate in fetal tissue in several animal species. Neurological, teratogenic, liver, and immune system effects have been reported in the offspring of animals orally exposed to hexachlorobenzene while they were pregnant.

no data available

The substance may have effects on the liver and nervous system. This may result in impaired functions of organs and skin lesions. This substance is possibly carcinogenic to humans. Animal tests show that this substance possibly causes toxic effects upon human reproduction.

Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying.

Little to no biodegradation was noted in biodegradation screening tests(1,3,4), in activated sludge(2,5), or in soil(6-8). Measurement of CO2 evolution from suspended soil cultures over a 14-day incubation period were as follows: 0.4% under aerobic conditions, 0.2% under anaerobic conditions(9).

BCF values of 2,700 to 4,800 were measured in carp exposed to 10 ug/L of hexachlorobenzene during an 8 week incubation period and BCF values of 1,600 to 3,900 were measured in carp exposed to 1 ug/L of hexachlorobenzene during an 8 week incubation period(1). Log BCF values in rainbow trout (Salmo gairdneri) were given as 3.7-4.3(2-4) and in fathead minnows (Pimephales promelas) and sunfish (Lepomis cyanellus) log BCF values of 4.21 and 4.34, respectively, were reported(3). After an 8-week exposure period of carp (Cyprinus carpio) to concentrations of 0.5 and 0.05 ug/L of hexachlorobenzene, the BCFs were 11,000-27,000 and 6,000-30,000, respectively(5). According to a classification scheme(6), these BCF values suggest that bioconcentration in aquatic organisms is very high, provided the compound is not metabolized by the organism(SRC).

A log Koc value of 5.5 (Koc of 3.2X10+5) was reported for hexachlorobenzene in freshwater river sediment(1). A log Koc value of 4.9 (Koc of 7.9X10+4) was reported for hexachlorobenzene in sediment obtained from the Ise Bay, Japan(2). Measured log Koc values of 3.6 (Koc of 4X10+3)(3) and 4.0 (Koc of 1X10+4)(4) were reported in soils. Log Koc values of 6.42 and 5.56 (Koc values of 2.6X10+6 and 3.6X10+5) were determined for two sediment layers from a lake(5). Hexachlorobenzene has measured log Koc value of 3.99 (Koc of 9.8X10+3) reported for soils(6). Hexachlorobenzene was found to desorb very slowly from sediment in water(7). According to a recommended classification scheme(8), these Koc values suggest that hexachlorobenzene is expected to be immobile in soil(SRC).

no data available

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

ADR/RID: UN2729 (For reference only, please check.)

IMDG: UN2729 (For reference only, please check.)

IATA: UN2729 (For reference only, please check.)

ADR/RID: HEXACHLOROBENZENE (For reference only, please check.)

IMDG: HEXACHLOROBENZENE (For reference only, please check.)

IATA: HEXACHLOROBENZENE (For reference only, please check.)

ADR/RID: 6.1 (For reference only, please check.)

IMDG: 6.1 (For reference only, please check.)

IATA: 6.1 (For reference only, please check.)

ADR/RID: III (For reference only, please check.)

IMDG: III (For reference only, please check.)

IATA: III (For reference only, please check.)

ADR/RID: Yes

IMDG: Yes

IATA: Yes

no data available

no data available

Depending on the degree of exposure, periodic medical examination is suggested.Do NOT take working clothes home.