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1111070-93-9

1111070-93-9 Structure

1111070-93-9 Structure
IdentificationBack Directory
[Name]

Kiss2 peptide
[CAS]

1111070-93-9
[Synonyms]

Kiss2 peptide
[Molecular Formula]

C63H84N16O12
[MOL File]

1111070-93-9.mol
[Molecular Weight]

1257.44
Chemical PropertiesBack Directory
[density ]

1.40±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka]

13.34±0.46(predicted)
[Sequence]

Phe-Asn-Phe-Asn-Pro-Phe-Gly-Leu-Arg-Phe-NH2
Hazard InformationBack Directory
[Uses]

Kiss2 peptide is a positive regulator of reproduction. Kiss2 peptide binds with its cognate receptor Kiss2R (GPR54) in COS-7 cells, activates PKA and PKC signaling pathways through Gas and Gaq proteins, and thus enhances the activity of cAMP response element-dependent luciferase (CRE-luc) and serum response element-dependent luciferase (SRE-luc)[1].
[References]

[1] Wang B, et al., Inhibitory action of tongue sole LPXRFa, the piscine ortholog of gonadotropin-inhibitory hormone, on the signaling pathway induced by tongue sole kisspeptin in COS-7 cells transfected with their cognate receptors. Peptides. 2017 Sep;95:62-67. DOI:10.1016/j.peptides.2017.07.014
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