ChemicalBook--->CAS DataBase List--->1217683-35-6

1217683-35-6

1217683-35-6 Structure

1217683-35-6 Structure
IdentificationBack Directory
[Name]

rac-Paroxetine-d4 Hydrochloride
[CAS]

1217683-35-6
[Synonyms]

2H4]- (±)-Paroxetine HCI
Paroxetine hydrochloride salt
rac-Paroxetine-d4 Hydrochloride
2H4]-Paroxetine hydrochloride salt
[2H4]- (±)-Paroxetine Hydrochloride
[Molecular Formula]

C19H17ClD4FNO3
[MOL File]

1217683-35-6.mol
[Molecular Weight]

369.851
Chemical PropertiesBack Directory
[Melting point ]

>82°C (dec.)
[storage temp. ]

Refrigerator
[solubility ]

Methanol (Slightly), Water (Slightly)
[form ]

Solid
[color ]

White to Pale Beige
Hazard InformationBack Directory
[Uses]

rac-Paroxetine-d4 Hydrochloride is a racemic labeled analogue of Paroxetine Hydrochloride (P205750), a selective serotonin reuptake inhibitor. Used as an antidepressant.
[in vivo]

Paroxetine (15 mg/kg/d; p.o.; 15 d) obviously attenuates the symptoms of collagen-induced arthritis (CIA) rats[2].

Animal Model:Collagen-induced arthritis (CIA) model in rats (around 14-day-old)[2]
Dosage:15 mg/kg
Administration:Oral gavage; once daily; 15 days
Result:Helped CIA rats to restore more body weight.
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