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1224095-25-3

1224095-25-3 Structure

1224095-25-3 Structure
IdentificationBack Directory
[Name]

L-Lysinamide, L-valyl-L-glutaminyl-L-arginyl-L-tryptophyl-L-leucyl-L-isoleucyl-L-valyl-L-tryptophyl-L-arginyl-L-isoleucyl-L-arginyl-
[CAS]

1224095-25-3
[Synonyms]

IDR 1002
L-Lysinamide, L-valyl-L-glutaminyl-L-arginyl-L-tryptophyl-L-leucyl-L-isoleucyl-L-valyl-L-tryptophyl-L-arginyl-L-isoleucyl-L-arginyl-
[Molecular Formula]

C79H130N26O13
[MOL File]

1224095-25-3.mol
[Molecular Weight]

1652.04
Chemical PropertiesBack Directory
[density ]

1.39±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

13.31±0.46(Predicted)
[color ]

White to off-white
[Sequence]

Val-Gln-Arg-Trp-Leu-Ile-Val-Trp-Arg-Ile-Arg-Lys-NH2
Hazard InformationBack Directory
[Description]

IDR 1002 is a synthetic cationic innate defense regulator peptide that increases the numbers of neutrophils and monocytes in mouse peritoneum and protects against S. aureus and E. coli infections in mice.
[Uses]

IDR-1002 is an anti-infective peptide that enhances the ability of human monocytes to migrate toward chemokines on fibronectin. IDR-1002 also induces adhesion and activation of β1-integrin, a mechanism that promotes monocyte recruitment[1].
[storage]

-20°C
[References]

[1] Madera L, et al. Synthetic immunomodulatory peptide IDR-1002 enhances monocyte migration and adhesion on fibronectin. J Innate Immun. 2012;4(5-6):553-68. DOI:10.1159/000338648
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