| Identification | Back Directory | [Name]
Piperazine, 2-[[4-(phenylmethoxy)phenyl]methyl]-5-(phenylmethyl)-, (2S,5S)- | [CAS]
1809167-48-3 | [Synonyms]
Antifungal agent 32
(2S,5S)-2-[[4-(Phenylmethoxy)phenyl]methyl]-5-(phenylmethyl)piperazine
Piperazine, 2-[[4-(phenylmethoxy)phenyl]methyl]-5-(phenylmethyl)-, (2S,5S)- | [Molecular Formula]
C25H28N2O | [MOL File]
1809167-48-3.mol | [Molecular Weight]
372.5 |
| Hazard Information | Back Directory | [Uses]
Antifungal agent 32 (compound 1a) is a potent antifungal agent. Antifungal agent 32 inhibits Candida albicans filamentation and biofilm formation. Antifungal agent 32 inhibits the morphological switching of Candida albicans and its adherence to epithelial cells. Antifungal agent 32 can be used for Candida albicans infections research[1]. | [References]
[1] Simon G, et al. Preventing Candida albicans biofilm formation using aromatic-rich piperazines. Bioorg Med Chem. 2020 Dec 1;28(23):115810. DOI:10.1016/j.bmc.2020.115810 |
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