| Identification | Back Directory | [Name]
6H-Benzofuro[3,2-c][1]benzopyran-6-one, 8-hydroxy-7-(1-piperidinylmethyl)- | [CAS]
2221801-50-7 | [Synonyms]
Polyketide synthase 13-IN-3
6H-Benzofuro[3,2-c][1]benzopyran-6-one, 8-hydroxy-7-(1-piperidinylmethyl)- | [Molecular Formula]
C21H19NO4 | [MOL File]
2221801-50-7.mol | [Molecular Weight]
349.38 |
| Hazard Information | Back Directory | [Uses]
Polyketide synthase 13-IN-3 (compound 41) is a polyketide synthase 13 inhibitor，with a MIC of 0.0625-0.125 μg/mL against the M. tuberculosis strain H37Rv[1]. | [References]
[1] Wei Zhang, et al. Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis. Part II. J Med Chem. 2019 Apr 11;62(7):3575-3589. DOI:10.1021/acs.jmedchem.9b00010 |
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