| Identification | Back Directory | [Name]
SHR5133 | [CAS]
2270943-23-0 | [Synonyms]
SHR5133
Imidazo[1,5-a]pyrazine-1,7(8H)-dicarboxamide, N7-(3-cyano-4-fluorophenyl)-5,6-dihydro-6-methyl-N1-[(1R)-2,2,2-trifluoro-1-methylethyl]-, (6S)- | [Molecular Formula]
C19H18F4N6O2 | [MOL File]
2270943-23-0.mol | [Molecular Weight]
438.38 |
| Hazard Information | Back Directory | [Uses]
SHR5133 is a highly potent, orally active HBV capsid assembly modulator. SHR5133 displays HBV DNA reduction (EC50=26.6 nM)[1]. | [References]
[1] Li X, et al. Discovery of SHR5133, a Highly Potent and Novel HBV Capsid Assembly Modulator. ACS Med Chem Lett. 2022;13(3):507-512. Published 2022 Feb 17. DOI:10.1021/acsmedchemlett.2c00002 |
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