| Identification | Back Directory | [Name]
1H-Pyrazole-5-carboxamide, N-[(1S)-2-[[2-fluoro-4-[(1S,2R)-1-methyl-3-(4-methyl-1-piperazinyl)-3-oxo-2-[(1-oxopropyl)amino]propyl]phenyl]amino]-1-(trans-4-methylcyclohexyl)-2-oxoethyl]-1-(1-methylethyl)- | [CAS]
2467732-95-0 | [Synonyms]
IL-17A modulator-3
N-[(2R,3S)-3-{3-fluoro-4-[(2S)-2-{[1-(propan-2-yl)-1H-pyrazol-5-yl]formamido}-2-[(1r,4S)-4-methylcyclohexyl]acetamido]phenyl}-1-(4-methylpiperazin-1-yl)-1-oxobutan-2-yl]propanamide
1H-Pyrazole-5-carboxamide, N-[(1S)-2-[[2-fluoro-4-[(1S,2R)-1-methyl-3-(4-methyl-1-piperazinyl)-3-oxo-2-[(1-oxopropyl)amino]propyl]phenyl]amino]-1-(trans-4-methylcyclohexyl)-2-oxoethyl]-1-(1-methylethyl)- | [Molecular Formula]
C34H50FN7O4 | [MOL File]
2467732-95-0.mol | [Molecular Weight]
639.8 |
| Hazard Information | Back Directory | [Uses]
IL-17A modulator-3 (compound 253) is a IL-17A modulator. IL-17A modulator-3 inhibits IL-17A/A with an IC50 value ＜10 μM. IL-17A modulator-3 can be used for the research of inflammation, cancer and autoimmune disease[1]. | [References]
[1] Fatheree, Paul R, et al. Amidoamide ligands as IL-17 modulators and their preparation. US20200247785. 2020. |
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