| Identification | Back Directory | [Name]
1,4-Naphthalenedione, 2-(6-chloro-3-pyridinyl)- | [CAS]
2521629-84-3 | [Synonyms]
Anti-infective agent 2
1,4-Naphthalenedione, 2-(6-chloro-3-pyridinyl)- | [Molecular Formula]
C15H8ClNO2 | [MOL File]
2521629-84-3.mol | [Molecular Weight]
269.68 |
| Hazard Information | Back Directory | [Uses]
Anti-infective agent 2 (compound 3k) shows antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC50 values of 0.07 and 2.20 μM, respectively. Anti-infective agent 2 shows antimycobacterial activity against Mycobacterium smegmatis with a MIC of 32 μg/mL[1]. | [References]
[1] Kalt MM, et al. Palladium-catalysed synthesis of arylnaphthoquinones as antiprotozoal and antimycobacterial agents. Eur J Med Chem. 2020 Dec 1;207:112837. DOI:10.1016/j.ejmech.2020.112837 |
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