| Chemical Properties | Back Directory | [Boiling point ]
559.4±50.0 °C(Predicted) | [density ]
1.181±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [pka]
10.73±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
KSK67 is a high-affinity dual sigma-2 and histamine H3 receptor antagonist, with Kis of 3.2, 1531, 101 nM for H3 receptor, sigma-1, sigma-2 receptor respectively. KSK67 can be used for research of nociceptive and neuropathic pain[1]. | [References]
[1] Szczepańska K, et al. Dual Piperidine-Based Histamine H3 and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain. J Med Chem. 2023 Jul 27;66(14):9658-9683. DOI:10.1021/acs.jmedchem.3c00430 |
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