| Identification | Back Directory | [Name]
1-Piperazinecarboxamide, N-(5-chloro-2-methoxyphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]- | [CAS]
260553-24-0 | [Synonyms]
RBP4 ligand-1
1-Piperazinecarboxamide, N-(5-chloro-2-methoxyphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]- | [Molecular Formula]
C18H18ClF3N4O2 | [MOL File]
260553-24-0.mol | [Molecular Weight]
414.81 |
| Hazard Information | Back Directory | [Uses]
RBP4 ligand-1 is a non-retinoid ligands for (RBP4) retinol-binding protein 4. The hRBP4SPA IC50 and RBP4-TTR FRET IC50 values are 0.23±0.11 and 0.13±0.12 μM in the radioligand binding assay and FRET assay, respectively[1]. | [References]
[1] Yingcai Wang, et al. Structure-assisted discovery of the first non-retinoid ligands for Retinol-Binding Protein 4. Bioorg Med Chem Lett. 2014 Jul 1;24(13):2885-91. DOI:10.1016/j.bmcl.2014.04.089 |
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