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262451-89-8

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262451-89-8 Structure

262451-89-8 Structure
IdentificationBack Directory
[Name]

SC 22716
[CAS]

262451-89-8
[Synonyms]

SC 22716,SC22716
1-[2-([1,1'-Biphenyl]-4-yloxy)ethyl]pyrrolidine
Pyrrolidine, 1-[2-([1,1'-biphenyl]-4-yloxy)ethyl]-
[Molecular Formula]

C18H21NO
[MDL Number]

MFCD05664740
[MOL File]

262451-89-8.mol
[Molecular Weight]

267.37
Chemical PropertiesBack Directory
[Melting point ]

58-60 °C(lit.)
[storage temp. ]

2-8°C
[solubility ]

DMSO: 22 mg/mL
[color ]

off-white
Safety DataBack Directory
[Safety Statements ]

22-24/25
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

SC-22716 is a potent, competitive, reversible inhibitor of human LTA4 hydrolase, with an IC50 of 0.20 μM. SC-22716 has potential for the research of inflammatory bowel disease (IBD) and psoriasis[1].
[References]

[1] Penning TD, et, al. Structure-activity relationship studies on 1-[2-(4-Phenylphenoxy)ethyl]pyrrolidine (SC-22716), a potent inhibitor of leukotriene A(4) (LTA(4)) hydrolase. J Med Chem. 2000 Feb 24;43(4):721-35. DOI:10.1021/jm990496z
Spectrum DetailBack Directory
[Spectrum Detail]

SC 22716(262451-89-8)1HNMR
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