| Identification | Back Directory | [Name]
Cyclohexanecarboxamide, 1-[5-[(3R)-3-methyl-4-morpholinyl]-3-(5-methyl-1H-pyrazol-3-yl)isothiazolo[4,5-b]pyridin-7-yl]- | [CAS]
2761194-15-2 | [Synonyms]
ATR-IN-17
Cyclohexanecarboxamide, 1-[5-[(3R)-3-methyl-4-morpholinyl]-3-(5-methyl-1H-pyrazol-3-yl)isothiazolo[4,5-b]pyridin-7-yl]- | [Molecular Formula]
C22H28N6O2S | [MOL File]
2761194-15-2.mol | [Molecular Weight]
440.56 |
| Hazard Information | Back Directory | [Uses]
ATR-IN-17 (compound 88) is a potent ATR kinase inhibitor. ATR-IN-17 shows good anticancer activity in LoVo cells, with an IC50 of 1 nM[1]. | [IC 50]
ATR | [References]
[1] Bo Shan, et al. Atr inhibitors and uses thereof. WO2022028598A1. |
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