| Identification | Back Directory | [Name]
Glycine, 2-[(3′,5′-dichloro-4′-methoxy[1,1′-biphenyl]-3-yl)methyl]-N-[[5-(5-methyl-2-furanyl)-1H-pyrazol-3-yl]carbonyl]-, (2R)- | [CAS]
2857113-78-9 | [Synonyms]
Glycine, 2-[(3′,5′-dichloro-4′-methoxy[1,1′-biphenyl]-3-yl)methyl]-N-[[5-(5-methyl-2-furanyl)-1H-pyrazol-3-yl]carbonyl]-, (2R)- | [Molecular Formula]
C25H21Cl2N3O5 | [MOL File]
2857113-78-9.mol | [Molecular Weight]
514.36 |
| Chemical Properties | Back Directory | [Boiling point ]
762.9±60.0 °C(Predicted) | [density ]
1.399±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [pka]
3.19±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
PLAP-IN-1 is a potent (IC50 = 32 nM) and selective PLAP inhibitor, with no detectable inhibition of tissue non-specific alkaline phosphatase (TNAP) activity. | [References]
[1] Bassi G, et al. Specific Inhibitor of Placental Alkaline Phosphatase Isolated from a DNA-Encoded Chemical Library Targets Tumor of the Female Reproductive Tract. J Med Chem. 2021 Nov 11;64(21):15799-15809. DOI:10.1021/acs.jmedchem.1c01103 |
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